Dramina method of application. Dramin motion sickness pills

Dramina is a drug from the group of H1-histamine receptor blockers used for motion sickness, sea and air sickness.

Active substance

Dimenhydrinate (Dimenhydrinate).

Release form and composition

Indications for use

  • prevention and elimination of symptoms of sea and air sickness;
  • Meniere's disease;
  • prevention and treatment of labyrinth and vestibular disorders (nausea, vomiting, dizziness).

Not indicated for the treatment of symptoms resulting from anticancer therapy.

Contraindications

  • increased individual sensitivity to the components of the drug;
  • acute exudative and vesicular dermatoses;
  • epilepsy.

Instructions for use Dramina (method and dosage)

Tablets should be taken orally before meals.

  • with sea and air sickness, the dose for children from 3 to 6 years old is from 0.25 to 0.5 tablets 2-3 times a day;
  • children from 7 to 12 years old are given half a tablet 2-3 times a day;
  • dose for children over 12 years old and adults - 1-2 tablets 2 or 3 times a day;
  • as a prophylactic and to eliminate the symptoms of vestibular and labyrinth disorders, children from 3 to 6 years old are prescribed from 0.25 to 0.5 tablets 2 or 3 times a day;
  • children from 7 to 12 years old - 0.5 tablets or 1 tablet 2-3 times a day;
  • children from 12 years old and adults - 1-2 tablets 2-3 times a day;
  • with Meniere's disease, children under 12 years old are given 0.5-1 tablet 2-3 times a day, children over 12 years old and adults - 1-2 tablets 2-3 times a day;
  • to prevent motion sickness, take one or two tablets 30 minutes before the start of the trip.

Maximum daily dose for adults - no more than 7 tablets. In this case, the duration of admission and the possibility of a second course of treatment should be determined by the doctor.

Side effects

Most often, when taking Dramina, a state of drowsiness occurs.

The following side effects are rarely caused:

  • dizziness, headache, fatigue, state of weakness, impaired concentration, nervousness, anxiety, insomnia;
  • nausea, vomiting, loss of appetite, dry mouth;
  • thickening of bronchial secretions, dryness of the mucous membranes of the throat and nose;
  • tachycardia, decreased blood pressure, hemolytic anemia;
  • bronchospasm, angioedema, skin rash.

In exceptional cases, there are:

  • difficulty urinating;
  • blurred vision;
  • disturbance of accommodation;
  • deterioration of night and color vision;
  • drug dermatitis.

Overdose

In case of an overdose of Dramina, the following symptoms occur:

  • redness of the face;
  • dry mouth, throat and nose;
  • difficulty breathing;
  • confusion.

Children may have seizures and hallucinations.

Overdose treatment includes symptomatic therapy, gastric lavage and saline laxative. For convulsions in children, phenobarbital or diazepam is prescribed.

Analogues

Analogues for the ATX code: Aviamarin, Gistafen, Dimebon, Fenkarol.

Do not make the decision to change the drug yourself, consult your doctor.

pharmachologic effect

  • Dimenhydrinate has the ability to inhibit the activity of certain hormones that provide communication between the brain and the vestibular apparatus. After the application of the drug, the signals coming from the vestibular apparatus to the central nervous system and causing nausea, dizziness, and other symptoms and signs of motion sickness and motion sickness.
  • It has a pronounced calming effect on the nervous system, eliminates dizziness, and also has antiemetic, anorexigenic (reduces appetite) and moderate anti-allergic effects.
  • Basic active ingredient quickly absorbed into the blood. The effect of the drug begins within 15-30 minutes after administration. The pharmacological effect can last from 3 to 6 hours. The drug is completely eliminated from the body within 24 hours.

special instructions

Prescribed with caution in bronchial asthma, convulsive syndrome, prostatic hyperplasia, cervical obstruction Bladder, angle-closure glaucoma, hyperthyroidism, cardiovascular disease, and stenosing peptic ulcer.

During therapy, you should refrain from drinking alcohol.

During pregnancy and breastfeeding

In the first trimester of pregnancy, the reception is contraindicated. In rare cases, it can be used for treatment in the second or third trimester of pregnancy, but this can be done only after the permission of a doctor who has previously assessed the likely risks.

Use during lactation is prohibited, since the drug is excreted in small amounts with breast milk.

In childhood

It is permissible to appoint from the age of three. At correct application the drug has practically no side effects.

drug interaction

In combination with sedatives, hypnotics, antidepressants, ethanol, the inhibitory effect on the central nervous system increases.

Dimenhydrinate may mask the ototoxicity of streptomycin and some other aminoglycoside antibiotics.

 The drug Dramina is able to block histamine receptors. It is recommended for symptoms of motion sickness, that is, for symptomatic manifestations of sea or air sickness. The main active ingredient is dimenhydrinate. It inhibits the action of certain hormones, which leads to the suspension of nerve impulses in the region of the vestibular apparatus of the brain. This has a calming effect on the central nervous system, the symptoms of dizziness are relieved, nausea and vomiting disappear. There is also a loss of appetite.

1. Pharmacological action

A drug that relieves the symptoms of motion sickness. It has a sedative, antiemetic and mild antiallergic effect. Can reduce appetite and eliminate dizziness.

The therapeutic effect of Dramina occurs 20 minutes after its oral administration and lasts for three to six hours.

2. indications for use

  • Treatment of disorders of the vestibular apparatus (with the exception of antitumor treatment);
  • Seasickness;
  • Treatment of labyrinth disorders (with the exception of antitumor treatment);
  • Airsickness;
  • Prevention of the occurrence of labyrinth disorders (with the exception of antitumor treatment);
  • Prevention of the occurrence of disorders of the vestibular apparatus (with the exception of antitumor treatment).

3. How to use

Recommended dosage of Dramina for:
  • children aged one to six years: 12.5-25 mg of the drug twice or thrice a day;
  • children aged seven to 12 years: 25-50 mg of the drug twice or thrice a day;
  • children over 12 years of age and adult patients: 50-100 mg of the drug twice or thrice a day;
  • prevention of seasickness: 50-100 mg of the drug half an hour before the trip.
  • the maximum dosage of Dramina: no more than 350 mg of the drug per day.
Application Features:
  • Dramina should be taken before meals;
  • During treatment, vigorous activity and driving of any category of vehicles should be avoided.

4. Side effects

  • Urinary system: difficulty in the process of urination;
  • Hematopoietic system: anemia;
  • Cardiovascular system: increased heart rate, drop in blood pressure;
  • Digestive system: loss of appetite, vomiting, dryness of the oral mucosa, nausea;
  • Central nervous system: headaches, weakness throughout the body, decreased ability to concentrate, increased nervous excitability, dizziness, drowsiness, increased fatigue, causeless anxiety, insomnia;
  • Sense organs: decrease in night vision, impaired ability of the pupil to change its lumen, decrease in color vision;
  • Respiratory system: dryness of the nasal mucosa, thickening of bronchial secretions;
  • Hypersensitivity reactions: , dermatitis, skin rashes, bronchial spasm.

5. Contraindications

  • epileptic seizures;
  • The use of Dramina at any stage of pregnancy;
  • Hypersensitivity to Dramina or its components;
  • Age less than one year of age;
  • The use of Dramina during breastfeeding;
  • Dermatoses in acute form.

6. During pregnancy and lactation

During pregnancy, the use of Dramina categorically contraindicated.

Dramina can be used only after the cessation of breastfeeding.

7. Interaction with other drugs

Simultaneous use of Dramina with:
  • Atropine, drugs of the catecholamine group, alcoholic drinks, sleeping pills, tricyclic antidepressants, barbiturate drugs or sedatives leads to an increase in their action;
  • drugs containing bismuth, painkillers, scopolamine or medicines, depressing the activity of the central nervous system, leads to visual impairment;
  • anticoagulant drugs and glucocorticosteroid drugs leads to a weakening of their action;
  • , Amikacin, Streptomycin, Viomycin or leads to irreversible hearing loss.

8. Overdose

Symptoms:
  • Respiratory system: slow breathing, shortness of breath, dryness of the mucous membrane of the nasal cavity, dryness of the mucous membrane;
  • Central nervous system: confusion, the appearance of hallucinations, convulsive syndrome;
  • Digestive system: dryness of the oral mucosa;
  • Cardiovascular system: redness of the face.
Specific antidote: no.

Overdose treatment:

  • Gastric lavage with a suspension of enterosorbents;
  • symptomatic treatment.
Hemodialysis: not effective.

9. Release form

Tablets, 50 mg - 5 or 10 pcs.

10. Storage conditions

Dramina is stored away from children.

11. Composition

12. Terms of dispensing from pharmacies

The drug is released without a prescription.

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* Instructions for medical use for Dramina are published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST


Dramina- effective remedy from motion sickness in transport for children and adults. This drug for motion sickness and nausea helps to block the signals transmitted by the vestibular apparatus to the central nervous system.
Blocks histamine H1 receptors and M-cholinergic receptors of the central nervous system. Depresses the vestibular apparatus of the inner ear, acting primarily on the otoliths, in high doses - on the semicircular canals. It has antiemetic, anorexigenic, sedative, moderate antiallergic effect, eliminates dizziness.
The effect of Dramina tablets occurs within 15-30 minutes, while the effect lasts for 3-6 hours.
Dramina's motion sickness remedy for cars, planes and other types of vehicles has a well-researched efficacy profile. It has been clinically proven that the active substance of this drug - dimenhydrinate - is the most effective in the fight against the symptoms of motion sickness, which include dizziness, nausea, vomiting, etc. (according to the study, its effectiveness reaches 72.9%).
Dramina has a high safety profile, so both adults and children can take this remedy for motion sickness in transport.
Taking pills for motion sickness at sea and on land can be carried out both as a preventive measure before a trip, and to eliminate already manifested symptoms of the disease, including: pallor, dizziness, stomach discomfort, nausea, vomiting, headache, drowsiness.
Clinical researches of the drug showed that Dramina tablets are a really effective and safe remedy for motion sickness in children, which can be used from the age of 3 years**. The drug is available in the form of tablets and is suitable for both treating the symptoms of motion sickness and for preventing them. To do this, it is enough to take a Dramina tablet 30 minutes before the trip. The active substance of this drug is dimenhydrinate, which blocks the transmission of signals to the brain that cause sensory conflict. Thanks to this, Dramina avoids such unpleasant symptoms of motion sickness for the child and his parents as nausea and vomiting.

Pharmacokinetics

After oral administration, the drug is well absorbed, distributed throughout organs and tissues. The effect of the drug appears after 15-30 minutes and lasts for 3-6 hours. Almost completely excreted from the body in the urine within 24 hours. Small amounts are excreted in breast milk.

Indications for use

A drug Dramina used for motion sickness in transport, sea and air sickness; for the prevention and treatment of symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting), with the exception of symptoms caused by anticancer therapy; Meniere's disease.

Mode of application

Tablets Dramina take orally, before meals:
- sea and air sickness: children from 3 to 6 years old - 1/4-1/2 tablets 2-3 times a day; children from 7 to 12 years old - 1/2-1 tablet 2-3 times a day; children over 12 years old and adults - 1-2 tablets 2-3 times a day;
- prevention and treatment of symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting), with the exception of symptoms caused by anticancer therapy: children from 3 to 6 years old - 1/4-1/2 tablets 2-3 times a day; children from 7 to 12 years old - 1/2-1 tablet 2-3 times a day; children over 12 years old and adults - 1-2 tablets 2-3 times a day;
- Meniere's disease: children under 12 years old - 1/2-1 tablet 2-3 times a day; children over 12 and adults
1-2 tablets 2-3 times a day.
The maximum daily dose for adults should not exceed 7 tablets. For the prevention of kinetosis, take 1-2 tablets 30 minutes before the trip.
The duration of the drug and the possibility of repeating the course of treatment - in agreement with the doctor.

Side effects

From the side of the central nervous system: dizziness, drowsiness, headache, general weakness, fatigue, impaired concentration, anxiety, nervousness, insomnia, rarely - weakening of night and color vision, blurred vision, disturbance of accommodation.
From the digestive system: dry mouth, loss of appetite, nausea, vomiting.
From the respiratory system: dryness of the mucous membrane of the nose and throat, thickening of bronchial secretions.
From the side of the cardiovascular system and blood: lowering blood pressure, tachycardia, hemolytic anemia.
Allergic reactions: skin rash, angioedema, bronchospasm, rarely - drug dermatitis.
Other: difficulty urinating.
All cases of side effects should be reported to the doctor.

Contraindications

:
Contraindications to the use of tablets Dramina are: hypersensitivity to the components of the drug, epilepsy, acute exudative and vesicular dermatoses, childhood up to 3 years, pregnancy, lactation.
With caution: convulsive syndrome, angle-closure glaucoma, prostatic hyperplasia, bronchial asthma, cardiovascular diseases, hyperthyroidism, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder neck obstruction.

Pregnancy

:
It is contraindicated to take pills Dramina in the first trimester of pregnancy.
It is possible to use the drug Dramina with extreme caution (II-III trimester), if the expected effect of therapy outweighs the potential risk to the fetus.
At the time of treatment should stop breastfeeding.

Interaction with other drugs

Dramina enhances the effects of atropine, tricyclic antidepressants, catecholamines, barbiturates, alcohol, sedatives and hypnotics, antipsychotics, weakens - corticosteroids, anticoagulants. Reduces response to apomorphine. Reduces the depressive effect of acetylcholine on the heart muscle. The combination with bismuth preparations, scopolamine, painkillers and psychotropic drugs increases the likelihood of visual impairment. Incompatible with ototoxic antibiotics (streptomycin, neomycin, viomycin, amikacin, kanamycin), because may mask the symptoms of ototoxicity and contribute to the development of irreversible hearing loss.

Overdose

:
Symptoms of drug overdose Dramina: dry mouth, nose and throat, redness of the face, slow and difficult breathing, confusion, in children - convulsions, hallucinations.
If these symptoms appear, you should immediately consult a doctor.
Treatment: gastric lavage with a suspension of activated charcoal (20-30 g), the appointment of a saline laxative (10-15 g of sodium sulfate), symptomatic therapy, for convulsions in children - phenobarbital (5-6 mg / kg), diazepam.

Storage conditions

Tablets Dramina should be stored at a temperature not exceeding 25 ° C, out of the reach of children.

Release form

Dramina - tablets 50 mg.
5 or 10 tablets in PVC / Al blister. One blister, along with instructions for use, is placed in a cardboard box.

Compound

:
1 tablet Dramina contains: active substance- dimenhydrinate 50 mg.
Excipients: lactose monohydrate - 112.53 mg; microcrystalline cellulose - 58.00 mg, magnesium stearate - 1.00 mg; povidone - 4.235 mg; crospovidone - 4.235 mg.

main parameters

Name: DRAMINA
ATX code: R06AX -

Dramina tablets are medicine, which is used for kinetosis (sickness in the sea and in airplanes). The drug belongs to the group of blockers of histamine H1 receptors and m-cholinergic receptors. Under the influence of the active active ingredient, the stimulation of the vestibular apparatus is inhibited. The drug has an antiemetic effect, calms the nervous system, eliminates dizziness and weakness against the background of fear. In addition, the drug has a mild anti-allergic effect.

After taking the tablet inside, the therapeutic effect develops after 15 minutes and lasts for 6 hours.

Method of application and dosage

Dramina tablets are taken orally before meals.

With therapeutic use, the frequency of administration can be 2-3 times a day, the recommended dose has age restrictions:

  • Patients over 12 years old: 50-100 mg each, the maximum allowable daily dose is 350 mg;
  • 7-12 years: 25-50 mg;
  • Children from 1 to 6 years: 12.5-25 mg.

During pregnancy and lactation

Dramina is contraindicated for use during pregnancy.

If it is necessary to use Dramina during lactation, breastfeeding should be stopped.

Side effects

Master in frequency side effect that causes Dramina is a state of drowsiness. Reviews about Dramine confirm that other side effects when taking the drug occur quite infrequently. Among them, the following negative effects of Dramina can be distinguished, reviews of the occurrence of which appear quite rarely:

  • dizziness, headache, fatigue, weakness, impaired concentration, nervousness, anxiety, insomnia;
  • nausea, vomiting, loss of appetite, dry mouth;
  • thickening of bronchial secretions, dryness of the mucous membranes of the throat and nose;
  • tachycardia, lowering blood pressure, hemolytic anemia;
  • bronchospasm, angioedema, skin rash.

Even more rarely, Dramina can cause difficulty urinating, blurred vision, disturbance of accommodation, impaired night and color vision, and drug-induced dermatitis.

With an overdose of the drug, symptoms such as redness of the face, dry mouth, throat and nose, difficulty breathing and confusion occur. Children may have seizures and hallucinations. Overdose treatment includes symptomatic therapy, gastric lavage and saline laxative. For convulsions in children, phenobarbital or diazepam is prescribed.

Overdose

Symptoms of an overdose of the drug Dramina: dry mouth, nose and throat, redness of the face, slow and labored breathing, confusion, in children - convulsions, hallucinations.

If these symptoms appear, you should immediately consult a doctor.

Treatment: gastric lavage with a suspension of activated charcoal (20-30 g), the appointment of a saline laxative (10-15 g of sodium sulfate), symptomatic therapy, for convulsions in children - phenobarbital (5-6 mg / kg), diazepam.

Contraindications

A contraindication to the appointment of Dramina may be the following condition:

  • The medicine should not be given to babies under one year of age.
  • A contraindication to Dramine is the child's hypersensitivity to the components of the remedy.
  • It is forbidden to use the drug for epilepsy.
  • In case of acute skin lesions - exudative dermatosis - Dramina's intake is excluded.
  • With herpes rashes in the acute phase, the use of the drug is not permissible.

Doctors do not recommend the use of Dramina during treatment with drugs that have a high ototoxicity (aminoglycosides) - this can lead to prolonged hearing loss. The most severe complication in this situation may be permanent deafness.

Due to the fact that Darmina has a local analgesic effect, taking the drug can mask initial symptoms acute appendicitis.

Interaction with other drugs

With simultaneous use with sedatives, hypnotics, antidepressants, ethanol, the inhibitory effect on the central nervous system increases.

With simultaneous use, dimenhydrinate can mask the ototoxicity of streptomycin and, apparently, other antibiotics of the aminoglycoside group.

Price

The price of Dramina is from 162 rubles. in Moscow

Analogues

"Dramina" is a fairly effective remedy that can be safely used both for the treatment of children and adult patients. If there is a history of contraindications described in the instructions, the medicine can be replaced. Drugs that can suppress the symptoms of kinetosis belong to different pharmacological groups. Antihistamines have a moderate effect on the nervous system and a minimum number of side effects.

The following drugs are effective analogues of Dramina tablets:

  • Dramamine
  • Bonin
  • Erius
  • Aviamarine
  • Ciel
  • Peritol
  • Telfast
  • Diazolin

From what this or that remedy helps, the specialist will tell the patient in detail. It is imperative to consult a doctor when choosing a drug for the symptoms of motion sickness for a child. It should be remembered that any drug can enhance or inhibit the effect of another drug.

Many people suffer from such a problem as motion sickness. Each long trip is given to them with great difficulty and causes a significant deterioration in well-being. With the help of special medicines, discomfort can be eliminated. "Dramina" is one of the effective antihistamines. It has a complex effect on the body, relieves the symptoms of motion sickness. If necessary, analogues of "Dramina" can be selected, having a similar effect or composition.

The drug "Dramina": description

The problem of motion sickness in transport - kinetosis - is familiar to many people since childhood. Vegetative disorder is associated with weakness of the vestibular apparatus. The presence of such a violation should not be a reason for refusing to travel. You can prevent the onset of symptoms of kinetosis if you take a special drug in a timely manner. For example, "Dramina" helps a lot. Instructions for use, patient reviews indicate that the drug begins to act quickly enough.

According to the annotation, the tablets are blockers of the m-cholinergic receptors of the nervous system (central). When ingested, the drug begins to inhibit the vestibular system in the inner ear. The drug has a sedative, antiemetic, antihistamine and anorexigenic effects. "Dramina" quickly eliminates dizziness when traveling in transport. Active substance medication - dimenhydrinate. Instructions for use indicate that the component is quickly and completely absorbed from the digestive tract.

Indications

  • with Meniere's pathology;
  • with sea (air) sickness;
  • if necessary, treatment of vestibular abnormalities caused by traumatic brain injury;
  • for the prevention of kinetosis.

"Dramina" is also used in pediatrics for the treatment of children from 1 year old. The dosage is determined depending on the age category. It must be selected by a doctor.

Application features

Do not use the drug in case of hypersensitivity to the components in the composition. This can lead to a deterioration in well-being and various allergic reactions. A contraindication to the use of "Dramina" tablets is acute dermatosis (vesicular or exudative), herpetic rash, epilepsy.

In some cases, the patient may be prescribed analogues. "Dramina" is usually well tolerated by the body when the dosage is observed. However, against the background of taking the medicine, it can develop as allergic reaction(urticaria, skin redness, itching), and indigestion (vomiting, loss of appetite). From the side of the nervous system, dizziness, anxiety, increased fatigue, decreased concentration, weakness may appear.

Effective analogues

"Dramina" is a fairly effective remedy that can be safely used both for the treatment of children and adult patients. If there is a history of contraindications described in the instructions, the medicine can be replaced. Drugs that can suppress the symptoms of kinetosis belong to different pharmacological groups. Moderate effect on the nervous system and a minimum number of side effects have

The following drugs are effective analogues of Dramina tablets:

  • "Dramamine".
  • "Bonin".
  • "Erius".
  • "Aviamarine".
  • "Ciel".
  • "Peritol".
  • Telfast.
  • "Diazolin".

From what this or that remedy helps, the specialist will tell the patient in detail. It is imperative to consult a doctor when choosing a drug for the symptoms of motion sickness for a child. It should be remembered that any drug can enhance or inhibit the effect of another drug.

"Aviamarin" - what kind of drug?

If necessary, to eliminate signs of sea (or air) sickness, the Aviamarine remedy is often used. Tablets begin to act within 15 minutes. The condition improves significantly, signs of kinetosis disappear. The active ingredient of the drug is dimenhydrinate, a blocker of histamine-sensitive receptors.

According to the instructions, tablets can be given to children over 6 years old. During the period of treatment, you need to adhere to a certain regimen for taking the medication. To suppress the symptoms of motion sickness in transport, adult patients (and children over 12 years old) are shown to take 1-2 tablets of Aviamarin. Babies from 6 to 12 years old are prescribed 25 mg (0.5 tablets). The dosage may be increased up to 50 mg. You need to take the medicine every 6-8 hours. Daily maximum dose for children 6-12 years old - 150 mg, for adults - 400 mg.