Miramistin spray instructions for use after. Miramistin - instructions for use for children, dosage, active ingredient, contraindications and reviews

Miramistin throat spray is a domestic antiseptic with an extremely wide scope. Gynecology, urology, traumatology, venereology, surgical practice - this is an incomplete list of areas in which this drug is considered indispensable.

In otorhinolaryngology, the drug is used to irrigate the throat, to wash the sinuses, in the treatment of otitis media.

The tool has obvious advantages for consumers who recommend using Miramistin for the throat for both children and adults.

In contact with

Composition and form of Miramistin in the form of a spray

Miramistin was created at the end of the Soviet era as an antiseptic for use in outer space. The resulting medicine turned out to be very simple in its composition:

• Benzyldimethyl ammonium chloride monohydrate - as an active substance;
• water - as an auxiliary substance.

Externally, the solution is a clear, colorless liquid, odorless and tasteless.

In the form of a throat spray, the drug is released in 150 ml plastic bottles.

Instructions for use for adults

When purchasing a spray at a pharmacy, the consumer receives a box with a bottle of the product (closed with a sealed cap) and a separately packed spray nozzle. Before irrigating the throat with Miramistin, you should prepare the bottle for work:

1. Open the vial.
2. Unpack the spray system.
3. Insert the atomizer with a long transparent tube inside the bottle.
4. Screw in the spray nozzle clockwise.
5. Move the spray tube from vertical position to horizontal.
6. Press the nozzle several times until the medicine begins to spray.

Instructions for use Miramistin for throat adults (in the form of a spray):

1. Take a few 2-3 sips of water before spraying.
2. Insert the spray tube into the mouth, point towards the left tonsil.
3. Press once.
4. Adjust the position of the spray tube towards the back of the throat.
5. Press once.
6. Aim the spray tube at the area of ​​the right tonsil.
7. Press once.

Thus, in one procedure, the patient must make 3 sprays on different areas of the throat mucosa. Depending on the intensity of the inflammatory process, the dosage can be adjusted - from 2 to 4 sprays at a time.

1. Pour the medicine into a tablespoon.
2. Gargle with a measured volume in the traditional way for 30 seconds.
3. Do not swallow the solution.
4. At the end of the procedure, spit out the liquid.

Miramistin for gargling does not need to be diluted!

How many times can Miramistin be sprayed into the throat of a child:

• Up to 6 years - single spray;
• up to 14 years - double spraying;
• over 14 years old - in an adult dosage.

From what age can children

The instructions for use of the Miramistin throat spray indicate the dosage for children from 3 years of age. Meanwhile, there are no contraindications for use in younger children. This allows us to consider the 3-year age limit conditional. It is generally accepted that from the age of 3, children begin to realize the meaning of the procedure, react more calmly to the introduction of a spray tube and to spraying. medicinal product.

Pediatricians prescribe Miramistin for sore throat in a child at any age.

The main problem is how to make sure that the remedy gets into the throat. There are 2 restrictions here:

• You can’t explain to the baby that you need to open your mouth to take the medicine;
• it is better not to allow Miramistin to be sprayed into the throat of newborns.

It is known that in babies up to a year, a sprayed substance in contact with the mucous respiratory tract can cause them to spasm, provoke difficulty in breathing.

Mom in the case of a baby should be guided by a simple rule: the main thing is that the medicine is in the mouth. Mixing with saliva, sooner or later the drug will spread through the mucous membrane of the throat, where it will have its direct effect.

How to spray Miramistin in the throat of a child? The most obvious and simple option is to sprinkle on the nipple and give it to the baby. However, today not everyone uses nipples.

Reviews of mothers who gave Miramistin to the baby in the throat contain, for example, the following recommendation: a spray tube may well interest a child who at this age likes to put everything in his mouth. Once the tube is in the baby's mouth, spritz it on the tongue or on the inside of the cheek. The medicine does not cause irritation, has no taste. As a rule, if spraying occurs "by chance", the baby tolerates the procedure well.

Application for children 1, 2, 3 years old

Spasm of the larynx or trachea as a result of contact with their mucous membranes of the drug can occur at a later age. If, for example, Miramistin is required to be sprayed into the throat of a child of 2 years old, and he does not know how to hold his breath, then they act by analogy with infants. You can splash on the tongue, on the inner surface of the cheek.

Is Miramistin possible during pregnancy in the 1st, 2nd, 3rd trimester

Instructions for use Miramistin for the throat does not contain any special recommendations for use in pregnant women. It is known that the drug is not absorbed from the mucous membranes. Some of it is swallowed with saliva. There is no information that the drug is absorbed in the digestive system.

Based on the available data, it can be concluded that Miramistin can be used during pregnancy in the throat in any trimester, but with caution and in moderate doses.

When breastfeeding

Miramistin is one of the few antiseptics approved for use during lactation. No information is available on whether specific studies have been conducted in lactating women. However, if we take into account the extremely low resorption of the substance at topical application, the probability of its penetration into breast milk zero.

What helps spray Miramistin

The drug is effective against:

• Bacteria, including those resistant to other antibiotics;
• fungi, including resistant species;
• viruses.

The high antimicrobial activity of the drug is associated with its relatively short period of use. In medical practice, it began to be used in the 1990s. The drug has been widely used since the 2000s. That is, Miramistin - by pharmacological standards new drug. That is why even hospital infections are sensitive to it.

The scope of the drug is wide. As part of complex therapy it helps with the following diseases:

• Inflammation of the mucous membrane of the respiratory tract;
• inflammation of the oral mucosa;
• inflammatory diseases genitourinary system both in women and men;
• fungal diseases of the skin;
• disinfection of burns, wounds;
• inflammatory processes in the joints.

In addition, the drug is used as a means for the prevention of the transmission of sexual infections.

Indications for use in sore throat

The drug has no analgesic effect. However, patients give good feedback about Miramistin, including use in diseases such as:

The drug is sprayed 3 times a day. The course of treatment is 4-7 days. You can use Miramistin for the throat not only as a spray, but also as a rinse solution.

The medicine is shown as antiseptic for the throat with acute angina. Active substance the drug increases the permeability of the shell of the microorganism, thins it, leading to destruction and subsequent death. Angina is most often caused, less often -. Miramistin is effective against both types of bacteria.

To date, no cases of bacterial resistance to the drug have been recorded. In accordance with the instructions for use, the Miramistin throat spray is effective even against hospital strains of bacteria “hardened” by quartz and antibiotics.

Upon contact with pus or blood, the drug does not reduce its activity.

Gargling with Miramistin is an alternative procedure.

1. Pour a full tablespoon of undiluted medicine.
2. Tilt your head back a little.
3. Pronounce a long sound "and-and-and."
4. Continue for 30 s.
5. Be sure to spit out the entire solution.

With angina, the medicine is used up to 4 times a day. The total duration is up to 10 days.

Miramistin for colds and flu

Miramistin is toxic to viruses, including those causing respiratory diseases. At the same time, the drug is not antiviral. His antiseptic action applies only to those viruses that have not penetrated into the cells of the mucosa and have not begun to replicate. On the flow viral infection in an already ill person, this drug does not work.

Despite this, the drug is indicated for flu and colds as a means of preventing the development of a bacterial infection. This is especially true in childhood, in which a bacterial complication occurs in almost 100% of cases.

In addition to antimicrobial activity, Miramistin stimulates the protective function of the throat mucosa:

• Increases local immunity;
• regeneration processes are improved;
• resistance of microorganisms to other antibiotics decreases.

Miramistin can be used not only for the throat, but also used 3-4 times a day. The course of treatment is up to 7 days.

Miramistin is indicated for otitis externa. For one reason or another (for example, from frequent exposure to water), a violation of the integrity of the skin occurs in the external auditory canal. Microbes get into these microcracks, which cause small inflammations. To combat these microbes, represented by bacteria and fungi, Miramistin is used in 2 ways:

• Zzapapyvayut in the ear 1-2 drops;
• moisten a cotton swab with medicine and lay it in the ear canal.

The procedure is repeated twice a day. If the patient does not have a fever, then otitis externa can be cured without the use of other means.

Instructions for use spray Miramistin recommends using the remedy for herpes. However, it should be noted that in terms of the effectiveness of the treatment of "cold" rashes on the mucous membranes, this drug is significantly inferior to special antiherpetic drugs based on acyclovir.

Miramistin spray analogues are cheaper

There are no direct analogues of Miramistin in the form of a throat spray.

Benzyldimethyl ammonium chloride - the development of Soviet specialists. Nowhere, except for Russia, the drug with this substance is not produced.

Antiseptic sprays based on other active ingredients are widely available in pharmacies. The cheapest of them:

However, if compared by the volume of the drug, then the drugs listed above will cost about the same, and sometimes more expensive, Miramistin. The exception is Chlorhexidine: it is about 10 times cheaper. However, the efficiency of these analogs is significantly lower, and taste qualities some of them, judging by consumer reviews, leave much to be desired.

What is better Miramistin

Miramistin and Chlorhexidine are similar in indications and method of application. Chlorhexidine has the following differences:

• Not recommended for children, pregnant and lactating women;
• has a bitter taste;
• often causes irritation.

Despite the more than attractive price of Chlorhexidine, it is better to use Miramistin for the treatment of the throat.

Miramistin or Tantum Verde

Miramistin and - drugs that have more different than common. Let's compare in the table.

Table 1. Comparative characteristics Miramistina and Tantum Verde

Miramistin

Tantum Verde

On the one hand, Tantum Verde has a more complex effect. On the other hand, many patients find it inconvenient to use the drug so frequently. In addition, despite the fact that the price of bottles of Tantum Verde and Miramistin is almost the same, the first remedy is enough for one course of treatment, and the second can be treated many times.

or Miramistin

Hexoral and Miramistin are drugs comparable in action and efficiency. They are approved for use by pregnant and lactating women, have no age restrictions on use.

Important differences for the consumer are presented in the table.

Table 2. Comparison of some consumer characteristics of Miromistin and Geksoral

Miramistin

Hexoral

From the point of view of the patient, Hexoral has important advantages - less frequent use of the drug and the possession of a weak analgesic effect. It should be noted that the cost of Geksoral is 2 times higher than the cost of Miramistin.

Miramistin or

Miramistin for the throat has obvious advantages over Furacilin:

• Spray method of applying the medicine;
• high antimicrobial activity;
• lack of taste;
• ease of use.

Nevertheless, many patients use Furacilin for gargling, they speak of it as an effective, inexpensive and familiar remedy.

As an antiseptic drug, otolaryngologists can prescribe Miramistin for the throat.

It is used in diseases associated with the penetration of pathogens into the human body. The disinfecting action is performed by the main active ingredient- benzyldemethyl ammonium chloride monohydrate.

The tool actively fights against a variety of pathogens of infectious inflammation. The spectrum of action includes viruses, bacteria and fungi. It can be prescribed to both children and pregnant women.

Miramistin from the throat: indications for use

At first, the antiseptic was used in astronautics. They treated the skin of astronauts, as well as equipment for disinfection from various microbes. Since viruses and bacteria multiply very quickly in a confined space, it made it possible to protect people from pathogenic microorganisms.

The active ingredient has a pronounced antiseptic property against gram-positive / gram-negative bacterial agents (with staphylococcus, streptococcus), aerobes and anaerobes.

It also destroys sexually transmitted infections (chlamydia, treponema, Neisseria, etc.). With immunodeficiency, the bactericidal composition successfully fights the manifestation of the disease.

With regard to fungi, the solution copes well with ascomycetes (genus Penicillium and Aspergillus), yeast and yeast-like fungi (genus Candida), pathogenic microorganisms that cause seborrheic dermatitis, etc.

Including liquid inhibits microbial associations that have developed resistance to chemotherapy. Often it is applied to prevent infection, violation of the integrity of the skin after a burn, injury, wounds. It activates the regenerative processes of the human body.

Due to hyperosmolar activity, the agent helps to perform the following actions:

• Relieves inflammation;
• Absorbs secretions;
• Forms a dry scab on the damaged area of ​​the body;
• Does not slow down epithelialization along the edges of the wound;
• Protects healthy cells;
• Does not cause irritation.

Why do doctors recommend this medicine? It is prescribed for inflammation of secretory or epithelial tissues caused by pathogens.

The drug is not absorbed through the skin and shell, therefore, it is suitable for administration in diseases requiring the use of bactericides and components that increase local immunity.

It is usually prescribed in the following cases:

inflammation in oral cavity. The instruction indicates that with stomatitis and periodontitis, the medication relieves redness, promotes the healing of sores, stops bleeding gums, and reduces pain. It is used to eliminate dental diseases.

Sinusitis. If inflammation in the adnexal cavities provokes the appearance of purulent exudate, swelling of the epithelium, then the ENT disinfects the secretory epithelium and cleanses the sinusoidal sinuses.

SARS. If a cold has a sore throat, there is inflammation of the auditory canals, then an antimicrobial mixture is recommended in order to speed up the patient's recovery. It destroys the infection and prevents infecting others if used as a preventive measure.

Burns, festering wounds. Festering affected areas of the body are treated with a solution, after which the healing process begins and the elimination of pus secretion begins. For burns, the medicine is applied to wounds to prevent the development of inflammation and suppuration.

Venereal diseases. An antiseptic is prescribed for syphilis, chlamydia, vulvovaginitis, etc. For prevention, it is administered by douching or rinsing after sexual contact.

note

That the method of application is individual, and the attending physician should select the dosage. It is not necessary to independently establish a therapeutic regimen of treatment.

How to dilute Miramistin for gargling?

How exactly you need to use an antibacterial composition for the treatment of ENT organs, the doctor will say.

Before using the liquid, it is important to read the annotation and look at the acceptable dosages for irrigation of the larynx in adults or children.
Source: site The course of therapy should not last longer than 10 days, so as not to cause dysbacteriosis in the mucous membranes of the pharynx. If discharged, then at home it is better to carry out instillation, rather than washing the nasal cavity. Thus, the patient will not be able to swallow a large amount of the substance.

Is it possible to rinse the larynx with a bactericide without dilution? Typically, the rinse is used for stomatitis and periodontitis. For one procedure, take 15 ml from the vial. Manipulations are repeated several times a day.

Treatment of the throat with Miramistin is carried out by spraying a ready-made antiseptic onto the affected membranes. It is available in several forms and with different percentages of the active ingredient. With a disease of the larynx, with tonsillitis or tonsillitis,

How to gargle with Miramistin?

1. Begin the procedure by tilting your head back.
2. In the process of rinsing, the sound “s” is pronounced, in which the liquid chemical composition penetrates to the remote areas of the tonsils, washing them well from all sides.
3. It is desirable to flush the throat with alternating anti-inflammatory drugs, for example, with a decoction of string, chamomile, salt water.
4. Only half an hour after the procedure is it allowed to eat or drink drinks.
5. To increase the effectiveness of medical manipulations, it is better to repeat the rinse at least three times a day.

Children should dilute the bactericide with boiled water in a ratio of 1:1. It is forbidden to swallow the product, therefore, if they do not know how to properly manipulate, then it is recommended to use a spray.

Miramistin: instructions for use of a throat spray for adults

The drug, which is released with a spray nozzle, makes it possible to irrigate mucous tissues by spraying it over a large area of ​​the oral cavity and pharynx.

Many people ask, is it possible to spray an antiseptic in the throat? Will it enter the stomach and cause side effects?

In fact, the instructions indicate that the aerosol is not forbidden to be sprayed into the throat area, since a small percentage of the substance, swallowed with saliva, will not provoke irritation in the gastrointestinal tract.

The finished product does not need to be diluted. The patient first activates the vial nebulizer by double pressing. After that, he begins to inject the spray onto the affected area. At one time, only 4 ml of volume is sprayed out of the bottle.

With purulent tonsillitis or other lesions of the ENT organs, it is necessary to press the sprayer three times. The frequency of daily administration and dosage is selected by the doctor.

Do I need to spit out the substance after injection? No, the administered dose is sufficient to destroy the infection, but not enough to develop side effects.

Miramistin for children with sore throat: how to apply?

At what age is it allowed to start therapeutic manipulations in the ENT organs with an antiseptic medication? The annotation states that it has no age restrictions. But this applies only to those cases when it is used as an external treatment of inflamed areas of the body.

Miramistin's solution is allowed to be used by children from 3 years of age, as babies already know how to rinse without swallowing the liquid.

A young child is given sprays or inhalations. It is also good to treat inflamed gums and the oral cavity with gauze dipped in a medicinal mixture.

In small children, the drug can cause irritation. Often they feel a burning sensation after its introduction. In the treatment of children 1-2 years old, a concentrated compound is diluted with water in a ratio of one to one.

How to use the treatment spray?

• A child of 3-6 years of age is recommended one spray at a time;
• Patients 7-14 years old are recommended to inject 2 doses;
• For adolescents over the age of fourteen, the dosage is increased to 15 ml of medicinal aerosol, that is, three times pressing.

How many times to spray an antibacterial substance per day? No more than 3-4 times. Aerosol sometimes provokes a slight burning sensation. It goes away 30 seconds after injection.

Miramistin for sore throat is suitable for the preparation of aerosol inhalations. To do this, it is good to buy an ultrasonic nebulizer that does not destroy antimicrobial properties, but, on the contrary, increases their effectiveness.

The device grinds the chemical compound to such a dispersion that it penetrates into the upper respiratory tract and settles on the walls of the larynx and pharynx, destroying pathogens.

Inhalations are not given to babies under 2 years old, because they cannot inhale the aerosol correctly. Passing through the nebulizer, it helps to cope with respiratory tract infections - bronchitis, tracheitis, tonsillitis, alveolitis.

It is prescribed as an additional cough medicine. The duration of one nebulizer inhalation is 5-15 minutes.

Use for children up to a year

Is it possible to buy a drug for one year old baby? Since it does not contain an unpleasant smell and taste, it is advised even for babies. It is allowed to spray medicine in the form of a spray on the tonsils for babies from 6 months old, but only on the recommendation of a pediatrician.

Important to remember

Do not spray antiseptic for children more than 3 times a day. During injection, hold your breath so that there is no spasm of the airways.

In children, an antibacterial compound can provoke mucosal dysbacteriosis, which will lead to inhibition of beneficial microflora and the development of a pathological one.

Pediatricians prescribe the solution to newborns up to a year, because it is not absorbed into the systemic circulation. Its action extends exclusively to the secretory and epithelial cover. If the throat is treated correctly, there will be no negative consequences for babies.

If we talk about rinsing the throat, then such a manipulation it is forbidden to use in the therapy of a one-year-old baby. Since there is high risk that he will swallow the solution or choke on it. And spraying can provoke a spasm of the trachea and bronchus.

Miramistin in the throat

What does Dr. Komarovsky say about the use of an antiseptic compound in the treatment of tonsil diseases in newborn babies?

Despite the fact that there are restrictions in the annotation - children under 3 years old, nevertheless it is prescribed for infants.

How to give a bactericide for diseases of the upper respiratory tract? Newborns lubricate the throat area with a soft cotton swab dipped in a solution. It is advisable to repeat the procedure three times a day.

A prerequisite is the preliminary cleaning of the baby's oral cavity. As soon as the child eats, his mouth is rinsed with water and then the medication is applied.

Use in pregnancy

Is it advisable to advise a bactericide for pregnant women? There are no significant studies that would show that the drug is contraindicated in the early stages. In any case, the instruction warns that you should consult your doctor before starting therapy.

If we talk about the introduction of the active component to a nursing mother, then it is not indicated here whether it is contraindicated during lactation. When breastfeeding, it is not dangerous because it does not penetrate the skin or mucous membranes, therefore it does not pass into milk.

In the 1st trimester of pregnancy, women can use it for external application to the skin or to the membranes of the upper respiratory tract. In the 2nd trimester and in the later stages, with diseases of the tonsils, after the permission of the doctor, it is recommended to rinse up to 5 times a day.

Questions to the doctor on the use of the drug

Misunderstandings often arise in connection with the antimicrobial spray in patients. To deal with them, consider the frequently asked questions.

Is it possible to swallow an antiseptic when irrigating the throat? No, it is intended for external application. When it enters the gastrointestinal tract, it causes irritation of the stomach. If a person cannot irrigate correctly without swallowing the liquid, then it is advisable to buy a spray. Miramistin or Chlorhexidine for throat which is better? There is no single answer. The antimicrobial properties of both agents are very high. An important difference between Chlorhexidine is that it is not and has a bitter taste. Also, when using it to wash the larynx in a person, plaque and tongue may darken for a while, due to staining of the bacterial flora. Chlorhexidine leaves a film on the surface of the secretory tissue, which allows you to maintain the antimicrobial property for a long time. Miramistin or Geksoral which is better for the throat? These are comparable substances, but Hexoral has a slight analgesic effect due to the content of menthol. You need to enter it only twice a day, one spray. But its cost is much higher. Can Miramistin burn the throat? A burn is really possible with a strong concentration of the active ingredient or prolonged retention in the mouth. It is important to follow the recommendations of the ENT so as not to burn the mucous membrane, especially when used by young children. Does your throat dry out? After irrigation, patients experience a burning sensation. This is a temporary effect that quickly passes. To avoid dryness of the cell layer, it is recommended to alternate washing the inflamed areas with a bactericide with herbal decoctions that have a softening effect.

Contraindications and possible side effects

If the patient is allergic to the active ingredient, then he should not be given an antimicrobial composition. Contraindication is also individual intolerance. In other cases, it is normally tolerated, without causing side effects and overdose symptoms.

Analogues: what can be replaced?

If, with a red throat caused by an infectious lesion, there are contraindications to the antimicrobial component, then it is necessary to look for an effective substitute.

First of all, doctors offer Chlorhexidine, which has similar properties. It's cheaper, but that doesn't make it any less effective.

For children, it is advised to take Octenisept, there is an opportunity to buy it in Europe. A suitable analogue would be Hexoral, Maxicold.

Miramistin in gynecology is used as a solution with a concentration of 0.01%, completely ready for use. It has an effective effect on different kinds microorganisms. Sometimes you can find this drug as an ointment, but its use is not so popular and is used more often in dermatology. Miramistin in solution is offered in packaging of 100 ml, 200 ml and 500 ml, and ointment - 15 g each.

Miramistin in gynecology is used in the following cases:

• inflammation in the vaginal cavity;
• fungal pathologies such as thrush;
• inflammation occurring in the mucous layer of the uterus;
• injured birth canal with suppuration of lesions, in the period after childbirth;
• treatment of sexual venereal diseases, treatment of postpartum infections.

The use of miramistin is allowed for pregnant women and is not contraindicated during breastfeeding.

The action of the drug

Miramistin has a unique feature of local action on the affected areas and without penetrating into the deeper layers of the tissue, it has a local antiseptic and disinfectant effect. Another feature of Miramistin solutions is the ability to reduce the resistance of resistant viruses to antibiotic exposure, penetrating into pathogenic microorganisms and thereby violating their intercellular septa. The drug is able to make any type of staphylococcus, streptococcus, Pseudomonas aeruginosa and Escherichia coli more vulnerable. Miramistin is successfully used as a means for the complex treatment of HIV and herpes.

Application in gynecology

There are different ways to use Miramistin, and the success of the entire treatment process will directly depend on the appropriateness of the method. The following are the most popular:

Should Miramistin be used during pregnancy?

During pregnancy, a woman undergoes significant hormonal changes. As a result, it is possible that various diseases caused by hormonal imbalance. The best remedy for the treatment of such disorders in pregnant women, without causing harm to any expectant mother nor her child, is Miramistin. The biological substances that make up its composition are not capable of harming the developing fetus throughout pregnancy. Nevertheless, women, especially pregnant women, should not prescribe Miramistin treatment on their own, since it is not able to be absorbed into the tissues and the active substance, accumulating on the treated area, can lead to an overdose of the drug. Despite the fact that this remedy is completely harmless, it is better to avoid such situations so as not to cause the development allergic reaction in a newborn. Use in the treatment of Miramistin during pregnancy, preferably in the form of napkins soaked in the substance. Douching during this period of time is undesirable, since deep irrigation of the vagina can provoke the penetration of the drug into the uterine cavity, and this should not be allowed during pregnancy.

Precautionary measures

Despite the fact that the active component of the drug has an exclusively local effect on the affected area and does not affect neighboring organs of the body, nevertheless Miramistin is a therapeutic agent and must be used correctly. When applying, you must adhere to the following:

• do not exceed the dosage;
• if an allergy to the drug occurs, it is necessary to stop using it and replace it with a similar one;
• if unpleasant sensations appear in the form of a burning sensation, do not stop processing, and soon such deviations will disappear.

Use of this medical device in medical practice for more than 40 years has not shown a single case of adverse deviations in the state of the body in pregnant women or during periods of breastfeeding. This, together with the high efficiency of Miramistin, has led to the high popularity of the remedy.

Colorless, clear liquid that foams when shaken. Pharmacotherapeutic group

Antiseptic. The codeATX: [ D08 AJ] .

Pharmacological properties

Miramistin has a wide spectrum of antimicrobial activity, including antibiotic-resistant hospital strains.

The drug has a bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae etc.), Gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp. etc.), aerobic and anaerobic bacteria, determined as monocultures and microbial associations, including hospital strains with multidrug resistance to antibiotics.

It has an antifungal effect on ascomycetes of the genus Aspergillus and the genus Penicillium, yeast (Rhodotorula rubra, Torulopsis gabrata etc.) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur) etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman- wolf Epidermophyton floccosum, microsporum gypsum, microsporum canis etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs. It has an antiviral effect, is active against complex viruses (herpes viruses, human immunodeficiency virus, etc.) Miramistin acts on pathogens of sexually transmitted diseases (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).

Prevents infection of wounds and burns. Activates regeneration processes. Stimulates protective reactions at the site of application, due to the activation of the absorption and digestion functions of phagocytes, potentiates the activity of the monocyte-macrophage system. It has hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry scab. Does not damage granulation and viable skin cells, does not inhibit marginal epithelialization.

It does not have a local irritating effect and allergenic properties. Pharmacokinetics

When applied topically, Miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Indications for use

Surgery, traumatology: suppuration prevention and treatment festering wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.

Obstetrics and Gynecology: prevention and treatment of suppuration of postpartum injuries, wounds of the perineum and vagina, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).

Combustiology: treatment of superficial and deep burns II and IIIA degree, preparation of burn wounds for dermatoplasty.

Dermatology-venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet.

Individual prevention of sexually transmitted diseases (syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis, etc.).

Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of a specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.

Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.

Otorhinolaryngology: complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis.

In children: at the age of 3 to 14 years, it is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.

Dosage and administration

The drug is ready for use.

Instructions for using the packaging with the spray nozzle:

Remove the cap from the vial. Remove the supplied spray nozzle from the protective packaging. Attach the spray nozzle to the vial. Activate the spray nozzle by pressing again.

Surgery, traumatology, combustiology. For prophylactic and therapeutic purposes, the surface of wounds and burns is irrigated, wounds and fistulous passages are loosely packed, gauze swabs moistened with the preparation are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

Obstetrics-gynecology. FROM for the prevention of postpartum infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), in childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours, for 5 days. When giving birth to women by caesarean section, immediately before the operation, the vagina is treated, during the operation, the uterine cavity and the incision on it, and in the postoperative period, tampons moistened with the drug are injected into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out in a course of 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of drug electrophoresis.

Venereology. For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse. Using a urological applicator, enter the contents of the vial into the urethra for 2-3 minutes: for men (2-3 ml), for women (1-2 ml) and into the vagina (5-10 ml). Treat the skin of the inner surfaces of the thighs, pubis, genitals. After the procedure, it is recommended not to urinate for 2 hours.

Urology. IN complex treatment urethritis and urethroprostatitis are injected into the urethra 2-3 ml of the drug 1-2 times a day, the course is 10 days.

Otorhinolaryngology. With purulent sinusitis - during the puncture, the maxillary sinus is washed with a sufficient amount of the drug. Tonsillitis, pharyngitis and laryngitis are treated by gargling and / or irrigation with a spray nozzle, 3-4 times pressing, 3-4 times a day. The amount of the drug per rinse is 10-15 ml.

In children. In acute pharyngitis and / or exacerbation of chronic tonsillitis, the pharynx is irrigated using a spray nozzle. Children 3-6 years old: a single press on the head of the spray nozzle (0.1 ml per irrigation) 3-4 times a day; children 7-14 years old double pressing (0.2 ml per irrigation) 3-4 times a day; children over 14 years old 3-4 times pressing (0.3-0.4 ml per irrigation), 3-4 times a day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission.

Dentistry. With stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug, 3-4 times a day.

Application features at individual groups of patients.

In patients with impaired liver and kidney function special studies have not been carried out. However, given that the drug does not penetrate the skin and mucous membranes, does not accumulate in the body and does not have a systemic effect, it is not required to change the therapeutic dose of the drug.

Elderly patients no special dosing regimen is required.

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Side effect

In some cases, a slight burning sensation may occur at the site of application, which disappears on its own, after 15-20 seconds, and does not require discontinuation of the drug. Allergic reactions.

Contraindications

Individual intolerance to the drug.