From what candles terzhinan instruction. Terzhinan candles: instructions, application, reviews

01.07.2017

A drug of combined composition, which is related to the group of antimicrobial drugs, is called "Terzhinan".

This medicine actively fights against various fungal infections and prevents decay. It is used in medicine, and in particular in the practice of treating gynecological diseases directly.

The pharmacological properties of the drug are determined by the biocomponents that make up its composition. "Terzhinan" has a clear effect against fungal, bacterial diseases, and is also effective against protozoa. In addition, it has a pronounced anti-inflammatory property.

The composition of the drug is formed by: ternidazole, neominicin sulfate, nystatin, prednisolone. Any of the components of the drug successfully fights certain groups of diseases.

Ternidazole - causes the death of protozoa, in particular Trichomonas and gardenel. That is why it is used to treat trichomoniasis and gardenelosis.

Nystatin is an antibiotic that has an antimicrobial effect. It tends to bind in the integument of fungal cells, causing biodamage in fungi and their further death.

Many species of fungi of the genus Candida, which cause candidiasis, are particularly susceptible to nystatin.

Neomycin is an antibiotic that is a representative of a group of organic substances in the structure of which there are amino sugar molecules. The action of neomycin is aimed at disrupting the formation of proteins in the cells of microorganisms that cause pathological processes.

In experiments conducted by scientists, it became known that the greatest susceptibility to neomycin is distinguished by:

• Corynebacterium
• Listeria
• Staphylococcus aureus
• Pseudomonas aeruginosa

Prednisolone is a drug of the glucocorticosteroid group. It has a clear anti-inflammatory, anti-allergic and anti-exudative effect. The anti-exudative effect is characterized by the prevention and reduction of the amount of edema.

In addition, directly in the composition of the tablets themselves are additional substances - geranium and clove oils, which, in turn, create the integrity of the vaginal tissues of the epithelium during all kinds of inflammatory and infectious processes. They also tend to maintain acid-base balance data in the vaginal environment. In addition, the presence of auxiliary means ensures better penetration active ingredients in the mucous membranes, since usually the protozoa are located inside the cells of the mucous membrane of the vulva and vagina, the brightest representatives are chlamydia and Trichomonas.

The drug is produced exclusively in the form of a tablet form. But since these tablets are intended for insertion into the vagina, they are sometimes called suppositories.

You can hear the name "Terzhinan 10" or "Terzhinan 6", the number means the number of tablets in one package and has no other meaning.

The drug "Terzhinan" is practically not absorbed by the cells of the human body.

What is treated with the drug "Terzhinan"

They are very popular among vaginal tablets, as they are the best method of dealing with the occurrence of inflammatory pathological processes that form in the female reproductive organs under the influence of harmful microorganisms. The trapped microorganisms begin to multiply actively and cause pathological processes.

These diseases are:

• vaginitis caused by pyogenic microflora
• colpitis, turning into a chronic stage, and from time to time recurrent
• dysbacteriosis occurring in the vagina
• trichomonas vaginitis
• candidal vaginitis caused by mixed pathogenic microflora

vaginal tablets prescribed immediately before the birth itself, as well as before the planned operations in the pelvic organs, as one of the means for prevention.

The use of "Terzhinan" helps to prevent the development of the disease - vaginitis.

Apply before the following manipulations and processes:

• birth process
• surgical abortion
• treatment of cervical pathologies
• x-ray with contrast agent
• before installing uterine contraceptives

"Terzhinan": instructions for use

In the prescription for the drug "Terzhinan" for cystitis, it is recommended to introduce vaginal tablets deep enough into the vagina, once a course of 10 days.

Introducing medicinal product, you should try not to touch the anus, in order to exclude the ingress of additional pathological microflora.

Before directly introducing the Terzhinan tablet into the vaginal opening, you must first lower it into clean water for 30-40 seconds or hold it in a wet palm for a couple of minutes. The time of administration of "Terzhinan" is very important, if the drug is administered during the daytime, then in this case it is necessary to take vertical position for a quarter of an hour. Naturally, the administration of the drug at bedtime will be best. The fact is that, in the morning, yellow discharge may appear after Terzhinan, which is a normal phenomenon during the course of a therapeutic course.

In addition, candidiasis, manifested in men by balanoposthitis and trichomoniasis, are considered common infections. With identified trichomoniasis and candidiasis, the course of therapy is not only a woman. Vaginal tablets "Terzhinan" are also used in the treatment of trichomoniasis in men. To normalize dysbacteriosis in the microflora of the vaginal environment and remove signs of obvious inflammation, it is necessary to prescribe a doctor who will accurately adjust the number of days of treatment.

Applying "Terzhinan" for thrush, the therapeutic course is doubled and is about 20 days. After completing the full course, it is necessary to pass tests and undergo some additional examinations to confirm recovery or to prescribe the duration of treatment.

"Terzhinan" with ureaplasma

Ureaplasmosis is an infectious disease caused by microorganisms - ureaplasmas. In the normal state, these microorganisms live on the mucous membranes of the genital organs of men and women. But in the event of a malfunction in the body's immunity, they begin to actively and uncontrollably multiply, which causes discomfort to the carrier. Despite the fact that with the disease ureaplasmosis, immunomodulatory drugs are used, their action does not always allow absolute results to be achieved.

In such cases, specific agents are prescribed that are aimed at combating bacteria and all kinds of fungi.

A valuable property of the medicinal product is that causing the death of fungal pathogens and pathogenic microbes, "Terzhinan" does not violate the microflora in the vaginal environment.

Specialists prescribe the drug "Terzhinan", as it successfully exerts its anti-inflammatory effect, and also fights against a wide spectrum pathogenic microorganisms.

The use of the drug "Terzhinan" during menstruation

Those who have problems with the microflora directly in the vagina are interested in the question of whether Terzhinan can be used during menstruation.

The instruction to the drug does not prohibit the use of the drug during critical days, but the quality of treatment will decrease significantly, since a large amount of the active substance will be washed out along with the excreted menstrual blood. At the same time, hygiene measures should be carefully observed.

"Terzhinan" and its use for the treatment of thrush

Recommended application medication for the treatment of thrush in women, which may be accompanied by the presence of secondary microflora. In addition, treatment should be started as early as possible if the symptoms are sufficiently pronounced.

In some cases, the drug is used to replace complex therapy previously used and found to be ineffective.

Specialists note a positive trend in the treatment of thrush with this drug, since after the course of therapy, no adverse reactions are noted.

"Terzhinan" during pregnancy and nursing mothers

The instructions do not describe situations prohibiting the use of the drug "Terzhinan" during pregnancy and lactation, but the supervision of a leading gynecologist is necessary.

"Terzhinan" in the early stages of pregnancy is strictly prohibited. In the following months of pregnancy, "Terzhinan" is prescribed when inflammatory processes occur directly in the vagina, caused by several pathogens of inflammation.

Not significantly adsorbed into the bloodstream, the likelihood of an overdose of the drug is excluded, as well as the possibility of getting through the umbilical cord and the fetoplacental barrier to the fetus.

"Terzhinan" candles used during pregnancy do not have an adverse effect on the unborn baby. In addition, an important criterion when choosing this drug for treatment is that it does not have the ability to enter into interaction reactions with other components of the medications used.

"Terzhinan" is also used during breastfeeding, the main thing is a correctly defined diagnosis, which really proves the need for therapy. A medicine is prescribed if other more gentle methods of treatment have not had the desired effect.

"Terzhinan" during lactation and pregnancy should be taken only after a mandatory consultation with your gynecologist and should not be used without an extra reason.

Contraindications

Like all medications, Terzhinan has certain limitations, which include:

• personal intolerance to the components of the drug
• the patient is under 16 years of age
• allergic reactions accompanied by itching, burning and discomfort

Side effects

This drug in extremely rare cases causes the manifestation of adverse reactions. Due to the fact that suppositories are used in regional therapy, the components included in their composition are not fully absorbed by the bloodstream.

This is what causes the manifestation of allergies at the site of use, characterized by burning, tingling, sometimes itching and soreness at the injection site of the drug.

In some cases, problems with body systems may occur, such as:

• atrophic changes in the mucous membrane
• delayed healing of wound surfaces
• delayed crack healing

Overdose

There is currently no information on an overdose of Terzhinan.

The fact is that the constituent substances of the drug have poor absorption into the human bloodstream, so the possibility of an overdose of the drug is considered impossible.

special instructions

The conducted studies have shown that in the drug "Terzhinan" there is an accumulation of active substances of the drug higher than the possible toxic concentrations. This implies that the pathogens of the infectious process are suppressed by the high content of substances in Terzhinan. In addition, there is a possibility of a synergistic effect, in other words, an increase in the action of each drug. Each individual substance that is part of Terzhinan has a narrow spectrum of action.

It is important to know that nystatin, and directly drugs containing it, have the ability to damage latex contraceptives.

Special attention should be paid to patients who have the following diseases:

• skeletal diseases
• hypertension
• heart failure

This is due to the fact that with the above pathological conditions should be wary of the use of glucocorticosteroids, which are part of "Terzhinan".

In addition, special care should be taken when using the drug for people who have the following diseases:

• peptic ulcers
• tuberculosis
• optic nerve atrophy
• persistent deficiency of thyroid hormones
• emotional turmoil
• neuromuscular disorders
• chronic neurological disorders
• diabetes
• myocardial infarction.

It is important to remember that Terzhinan and alcohol do not combine.

Terzhinan - an updated description of the drug, you can read the contraindications, side effects, prices in pharmacies on Terzhinan. Useful reviews about Terzhinan -

combination drug for local application in gynecology.
Preparation: TERZHINAN
The active substance of the drug: comb. drug
ATX encoding: G01BA
CFG: A drug with antibacterial, antiprotozoal, antifungal and anti-inflammatory action for topical use in gynecology
Registration number: P No. 015129/01
Date of registration: 21.07.08
The owner of the reg. Award: Laboratoires BOUCHARA-RECORDATI (France)

Terzhinan release form, drug packaging and composition.

Tablets for vaginal use
1 tab.
ternidazole
200 mg
neomycin sulfate
100 mg
nystatin
100 thousand units
prednisolone
3 mg

Excipients: corn starch, lactose, anhydrous silicon dioxide, talc, magnesium stearate, sodium lauryl sulfate, povidone, fragrance.

6 pcs. - cellular contour packaging (1) - packs of cardboard.
10 pieces. - cellular contour packaging (1) - packs of cardboard.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action Terzhinan

Combined preparation for local use in gynecology. The action of the drug is due to the properties of its constituent components.

Ternidazole, an imidazole derivative, has a trichomonacid effect and is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin sulfate is a broad-spectrum antibiotic from the aminoglycoside group.

Nystatin is an antifungal antibiotic from the group of polyenes, highly active against fungi of the genus Candida.

Prednisolone is a glucocorticoid that has a pronounced anti-inflammatory effect.

The composition of the excipient ensures the integrity of the vaginal mucosa and the constancy of pH.

Pharmacokinetics of the drug.

Studies of the pharmacokinetics of the drug Terzhinan were not conducted due to low systemic absorption.

Indications for use:

Treatment of vaginitis caused by microorganisms sensitive to the drug:

bacterial vaginosis;

Bacterial vaginitis caused by banal pyogenic or conditionally pathogenic rod microflora;

Trichomoniasis of the vagina;

Vaginitis caused by fungi of the genus Candida;

Mixed vaginitis.

Prevention of vaginitis:

Before gynecological operations;

Before childbirth or abortion;

Before and after the installation of the IUD;

Before and after diathermocoagulation of the cervix;

before hysterography.

Dosage and method of application of the drug.

Assign 1 vaginal tablet / day at bedtime. The average duration of the course of therapy is 10 days; in case of confirmed mycosis, it can be increased up to 20 days. Do not stop treatment during menstruation.

Before insertion into the vagina, the tablet should be held in water for 20-30 seconds.

Side effects of Terzhinan:

Local reactions: rarely - burning sensation, local irritation (especially at the beginning of therapy).

Other: extremely rare - allergic reactions.

Contraindications to the drug:

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation.

It is possible to use Terzhinan during pregnancy and lactation ( breastfeeding) according to indications.

Special instructions for the use of Terzhinan.

It is necessary to conduct simultaneous treatment of the sexual partner because of the risk of re-infection.

Drug overdose:

Due to the low degree of absorption into the systemic circulation, overdose is unlikely.

Interaction of Terzhinan with other drugs.

clinically significant drug interaction the drug Terzhinan with other drugs has not been identified.

Conditions of sale in pharmacies.

The drug is dispensed by prescription.

Terms of the storage conditions of the drug Terzhinan.

The drug should be stored at room temperature. Shelf life - 3 years.

Terzhinan is a drug with an antibacterial, anti-inflammatory effect, in addition, the drug has an antiprotozoal, antifungal effect. The drug is used topically in gynecology. For readers of "Popular about Health" I will present instructions for the use of this pharmaceutical product.

So, Terzhinan's instruction:

Composition and form of release

Terzhinan is produced by the pharmaceutical industry in light yellow vaginal tablets, they are flat, their shape is oblong, there is a chamfer, and there is also an engraving in the form of a "T" on both sides. The active substances of the drug are as follows: ternidazole, prednisolone sodium metasulfobenzoate, neomycin sulfate, and nystatin is also present.

Terzhinan contains auxiliary substances: wheat starch, magnesium stearate is added, lactose monohydrate in the right amount, colloidal silicon dioxide, sodium carboxymethyl starch is present.

pharmachologic effect Terzhinan

The pharmaceutical preparation Terzhinan is a combined remedy, as it contains several active compounds. Use this tool in gynecological practice. The drug has different actions: antimicrobial, antifungal, anti-inflammatory, antiprotozoal, in addition, when introduced into the vagina, it ensures the integrity of the mucous membrane and maintains a constant pH.

One of the active ingredients is ternidazole, an antifungal pharmaceutical belonging to the group of imidazole derivatives. This compound reduces the biosynthesis of ergosterol, changes the structure of the cell membrane and its properties, and also has a trichomonacid effect. This component is active against Gardnerella spp., as well as other anaerobic bacteria.

Another active substance vaginal tablets is represented by neomycin - a broad-spectrum antibiotic belonging to the aminoglycoside group. It acts bactericidal, that is, it causes the death of pathogenic microorganisms, in particular: Staphylococcus, Shigella boydii, Streptococcus pneumoniae, Escherichia coli, Shigella dysenteriae, and Shigella sonnei, in addition, Proteus spp., Shigella flexneri.

The next active substance of the drug is represented by the antifungal antibiotic nystatin, it belongs to the group of polyenes. It is highly effective against Candida fungi, slows down their development, and also helps to change the permeability of cell membranes.

An analogue of hydrocortisone is prednisolone, a hormonal agent that has a clear anti-inflammatory effect, has an anti-allergic effect, and this compound also has an anti-exudative effect. Due to the combined action of all of the above active components Terzhinan is used to treat certain gynecological pathologies, as well as for prevention.

What treats Terzhinan?

Terzhinan's indications include the treatment of vaginitis, which is caused by bacteria sensitive to the pharmaceutical preparation, including bacterial and mixed vaginitis, vaginal trichomoniasis, and inflammation of the vagina caused by Candida fungi.

In addition, the indications for the use of Terzhinan contain information about its use for prophylactic purposes against vaginitis, as well as urogenital infections before gynecological surgery, before hysterography, before childbirth, before abortion, before installing an intrauterine device.

Contraindications for use

Terzhinan is a contraindication for hypersensitivity to any of the compounds of this medication.

Application Terzhinan, dosage

The drug Terzhinan is intended for vaginal administration. In this case, it is recommended to introduce one tablet deep enough into the vagina, while the woman should be in a prone position. Better medicine use before bed.

Before direct administration, the tablet should be held for twenty seconds in warm water, and after administration dosage form it is important to lie down for at least ten minutes. Usually, the therapeutic course lasts ten days, and for prophylactic purposes, the medication is prescribed for six days.

Side effects

Side effects of Terzhinan are possible, which will be expressed in the form of a burning sensation, itching, some irritation in the vaginal area. As for systemic negative manifestations, they will be expressed in the form of allergic reactions.

Overdose Terzhinan

Due to the low absorption of the medicinal pharmaceutical preparation, the occurrence of an overdose is unlikely. In case of accidental swallowing of tablets, vomiting should be promptly provoked. If then the patient feels unwell, any other symptoms join, then it is recommended to seek qualified help from the medical staff.

special instructions

In the case of therapeutic measures for vaginitis, trichomoniasis, it is definitely recommended to conduct simultaneous treatment of sexual partners. Instructions for use informs that therapy should not be canceled during menstruation.

How to replace Terzhinan?

Currently, Terzhinan vaginal tablets have no analogues.

Conclusion

Before carrying out treatment with Terzhinan, it is recommended to consult a gynecologist.

Registration number: P N015129/01

Trade name: TERZHINAN

Dosage form: vaginal tablets

COMPOSITION for 1 tablet

Active ingredients:

Ternidazole…………………………………………..0.2 g
Neomycin sulfate ………………………………...0.1 g or 65000 IU
Nystatin ……………………………………………100,000 IU
Prednisolone sodium metasulfobenzoate……….. 0.0047 g,
equivalent to prednisone ……………………....0.003 g

Excipients:

DESCRIPTION

Tablets are light yellow in color with possible inclusions of darker or lighter shades, flat, oblong in shape with a chamfered edge and printed in the form of the letter "T" on both sides.

PHARMACOTHERAPEUTIC GROUP
Combined antimicrobial agent (antibiotic-aminoglycoside + antimicrobial and antiprotozoal agent + antifungal agent + glucocorticosteroid).

ATX code:

PHARMACOLOGICAL PROPERTIES

Combined preparation for local use in gynecology. It has an antimicrobial, anti-inflammatory, antiprotozoal, antifungal effect; ensures the integrity of the vaginal mucosa and the constancy of pH.

Ternidazole- an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (an integral part of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect, it is also active against anaerobic bacteria, in particular gardnerella.

Neomycin- a broad-spectrum antibiotic from the group of aminoglycosides. It acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; against Streptococcus spp., inactive.
Microbial resistance develops slowly and to a small extent.

Nystatin- an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisolone- dehydrated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

INDICATIONS FOR USE

Treatment of vaginitis caused by microorganisms sensitive to the drug, including:

bacterial vaginitis;
- trichomoniasis of the vagina;
- vaginitis caused by fungi of the genus Candida;
- mixed vaginitis.

Prevention of vaginitis, including:

Before gynecological operations;
- before childbirth and abortion;
- before and after the installation of intrauterine devices;
- before and after diathermocoagulation of the cervix;
- before hysterography.

CONTRAINDICATIONS

Hypersensitivity to any component of the drug.

PREGNANCY AND BREASTFEEDING

It is possible to use the drug from the second trimester of pregnancy.
The use of the drug in the first trimester of pregnancy and during lactation is possible only in cases where the potential benefit to the mother outweighs the risk to the fetus or infant.

METHOD OF APPLICATION AND DOSES

For vaginal use.
One tablet is injected deep into the vagina in the "lying" position at bedtime. Before insertion into the vagina, the tablet should be held in water for 20-30 seconds.
After the introduction it is necessary to lie down for 10-15 minutes.
The average duration of the treatment course of therapy is 10 days; in case of confirmed mycosis, it can be increased up to 20 days; the average duration of the prophylactic course is 6 days.

SIDE EFFECT
Burning sensation, itching and irritation in the vagina (especially at the beginning of treatment).
In some cases, allergic reactions are possible.

OVERDOSE
There are no data on cases of overdose.

INTERACTION WITH OTHER DRUGS
Not found.

SPECIAL INSTRUCTIONS

In the case of treatment of vaginitis, trichomoniasis, simultaneous treatment of sexual partners is recommended.
Do not stop treatment during menstruation.

RELEASE FORM

Vaginal tablets.

6 or 10 tablets per strip (aluminum foil), one strip with instructions for use is packed in a cardboard box.

BEST BEFORE DATE

3 years. Do not use after the expiration date.

STORAGE CONDITIONS

Store at a temperature not exceeding 25 °C.
Keep out of the reach of children.

TERMS AND CONDITIONS OF DISCOUNT FROM PHARMACIES

On prescription.

BOUCARD-RECORDAT Labs
68, rue Marjolin 92300
Levallois-Perret, France

Produced:
SOFARTEX
21, rue du Presso, 28500 VERNOUYER, France

Complaints about the quality of the drug should be sent to:

RUSSIA 123610 Moscow,
Krasnopresnenskaya emb. 12,
WTC, "International-2"

Terzhinan is a combined hormonal agent that is applied topically in gynecology. The composition of the drug includes:

• Neomycin - 100 mg;
• ternidazole - 200 mg;
• prednisolone - 3 mg;
• nystatin - 100,000 units.

Terzhinan has one release form - these are yellow tablets (candles) for vaginal use. Pack of 6 or 10 pieces.

Description of the drug

Terzhinan vaginal tablets, due to the combination of substances that it contains, have several effects:

• Neomycin is a broad-spectrum antibiotic that eliminates many of the bacteria that infect the female genital tract.
• Ternidazole - the action of the substance is aimed at eliminating the focus of trichomonas and gardnerelia.
• Prednisolone is a hormone from the group of glucocorticosteroids that acts as an anti-inflammatory agent.
• Nystatin is an antifungal drug, especially active against fungi of the genus candida.

Indications for use

Terzhinan during pregnancy and lactation has the same method of application as in other conditions. However, do not forget that pregnant women should receive treatment under the strict supervision of a doctor.

Terzhinan vaginal suppositories have a variety of indications for use:

• Bacterial vaginitis (inflammation of the vagina) with purulent discharge;
• vaginitis caused by Trichomonas;
• colpitis;
• ureaplasmosis genital;
• gardnerelez;
• thrush (candidiasis of the vagina);
• mixed vaginitis (has several different pathogens);
• inflammation of the appendages (used in combination with other drugs);
• prevention of inflammation before and after surgical interventions;
• condition after treatment of cervical erosion;
• prevention of inflammation after the installation of the spiral.

Terzhinan vaginal tablets can be administered during menstruation. The drug has indications for use during pregnancy and lactation.

Contraindications for use

Terzhinan should not be taken with allergic reactions and individual intolerance to any of its components. If such a condition is detected, it is necessary to replace the drug.

Overdose and side effects

Considering that the drug Terzhinan acts locally and practically does not enter the bloodstream, an overdose is impossible and has not been observed.

Side effects:

• Burning in the vagina and on the labia;
• redness of the vagina;
• itching at the injection site.

If these symptoms occur in the early stages of treatment, you can continue to use the drug.

Instructions for use Terzhinan

Tablets are inserted deep into the vagina, preferably at bedtime, 1 time per day. Before the introduction according to the instructions, it is recommended to soak in water for 30 seconds. In case of violation of the microflora and the inflammatory process in the genitals of a woman, the treatment takes 10 days.

Terzhinan with thrush must be received within 20 days.

special instructions

The man (sexual partner) should receive antibiotic treatment at the same time as the woman. This will prevent the recurrence of the infection. During treatment, sexual rest is desirable.

With menstruation and its delay, the drug is not stopped.

Terzhinan and alcohol. The effect of the drug is not affected by alcohol intake.

Drug analogues

Terzhinan's analogues do not contain an identical composition. If necessary, you can combine vaginal antibiotics and antifungal drugs. For example, Metronidazole (Gravagin) and Fluconazole. The annotation for these drugs contains detailed description way of application.