Terzhinan is a hormonal drug or not. How to put candles terzhinan
It has anti-inflammatory and anti-allergic effect, suppresses exudation in the focus of inflammation.
Terzhinan has proven itself in the treatment of vaginal dysbacteriosis. Thanks to a well-thought-out combination of components medicine is active against the most characteristic of the vagina of opportunistic microflora and prevents the growth and reproduction of candida. The presence in the composition of prednisolone, a powerful anti-inflammatory agent, determines the effectiveness of the drug in bacterial or yeast vulvovaginitis. Associated infections are another specialization of Terzhinan. As a rule, in patients of a dermatovenereologist who applied for a specific infection, several more associated infections are detected. In such situations, it is not recommended to prescribe only systemic antibiotic therapy: drugs that have a local effect on the vaginal microflora are also needed. And Terzhinan comes in very handy with its anti-inflammatory and antibacterial properties. The drug is also used during preoperative preparation before cryodestruction, excision of the cervix, conization, cauterization of erosion - it is prescribed for 10 days before the upcoming procedure. This is done to suppress the inflammatory process accompanying the underlying disease in order to prevent morphological changes in the epithelium of the cervix and vaginal mucosa.
Pharmacology
Combined preparation for local use in gynecology. It has an antimicrobial, anti-inflammatory, antiprotozoal, antifungal effect; ensures the integrity of the vaginal mucosa and the constancy of pH.
Ternidazole - an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (an integral part of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect, it is also active against anaerobic bacteria, in particular Gardnerella spp.
Neomycin is a broad-spectrum antibiotic from the aminoglycoside group. It acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; inactive against Streptococcus spp. Microbial resistance develops slowly and to a small extent.
Nystatin is an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.
Prednisolone is a dehydrated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.
Pharmacokinetics
Data on the pharmacokinetics of the drug Terzhinan are not provided.Release form
Vaginal tablets are light yellow in color, with possible inclusions of darker or lighter shades, flat, oblong in shape, with chamfered edges and printed in the form of the letter "T" on both sides.
Excipients: wheat starch - 264 mg, lactose monohydrate - q.s. up to 1.2 g, colloidal silicon dioxide - 6 mg, magnesium stearate - 10 mg, sodium carboxymethyl starch - 48 mg.
6 pcs. - strips (1) - packs of cardboard.
10 pieces. - strips (1) - packs of cardboard.
Dosage
For vaginal administration.
1 tablet is injected deep into the vagina in the supine position at bedtime. Before the introduction of the tablet should be held in water for 20-30 seconds. After the introduction, it is necessary to lie down for 10-15 minutes.
The average duration of the treatment course is 10 days; in case of confirmed mycosis, the duration of treatment can be increased up to 20 days; the average duration of the prophylactic course is 6 days.
Overdose
There are no data on cases of overdose.
Interaction
No drug interactions with Terzhinan have been identified.
Side effects
Local reactions: rarely - burning sensation, itching and irritation in the vagina (especially at the beginning of therapy).
Others: in some cases - allergic reactions.
Terzhinan - an updated description of the drug, you can read contraindications, side effects, prices in pharmacies for Terzhinan. Useful reviews about Terzhinan -
Combined preparation for local use in gynecology.
Preparation: TERZHINAN
The active substance of the drug:
comb. drug
ATX encoding: G01BA
CFG: A drug with antibacterial, antiprotozoal, antifungal and anti-inflammatory action for topical use in gynecology
Registration number: P No. 015129/01
Date of registration: 21.07.08
The owner of the reg. Award: Laboratoires BOUCHARA-RECORDATI (France)
Terzhinan release form, drug packaging and composition.
Tablets for vaginal use
1 tab.
ternidazole
200 mg
neomycin sulfate
100 mg
nystatin
100 thousand units
prednisolone
3 mg
Excipients: corn starch, lactose, anhydrous silicon dioxide, talc, magnesium stearate, sodium lauryl sulfate, povidone, fragrance.
6 pcs. - cellular contour packaging (1) - packs of cardboard.
10 pieces. - cellular contour packaging (1) - packs of cardboard.
The description of the drug is based on the officially approved instructions for use.
Pharmacological action Terzhinan
Combined preparation for local use in gynecology. The action of the drug is due to the properties of its constituent components.
Ternidazole, an imidazole derivative, has a trichomonacid effect and is also active against anaerobic bacteria, in particular Gardnerella spp.
Neomycin sulfate is a broad-spectrum antibiotic from the aminoglycoside group.
Nystatin is an antifungal antibiotic from the group of polyenes, highly active against fungi of the genus Candida.
Prednisolone is a glucocorticoid that has a pronounced anti-inflammatory effect.
The composition of the excipient ensures the integrity of the vaginal mucosa and the constancy of pH.
Pharmacokinetics of the drug.
Studies of the pharmacokinetics of the drug Terzhinan were not conducted due to low systemic absorption.
Indications for use:
Treatment of vaginitis caused by microorganisms sensitive to the drug:
bacterial vaginosis;
Bacterial vaginitis caused by banal pyogenic or conditionally pathogenic rod microflora;
Trichomoniasis of the vagina;
Vaginitis caused by fungi of the genus Candida;
Mixed vaginitis.
Prevention of vaginitis:
Before gynecological operations;
Before childbirth or abortion;
Before and after the installation of the IUD;
Before and after diathermocoagulation of the cervix;
before hysterography.
Dosage and method of application of the drug.
Assign 1 vaginal tablet / day at bedtime. The average duration of the course of therapy is 10 days; in case of confirmed mycosis, it can be increased up to 20 days. Do not stop treatment during menstruation.
Before insertion into the vagina, the tablet should be held in water for 20-30 seconds.
Side effects of Terzhinan:
Local reactions: rarely - burning sensation, local irritation (especially at the beginning of therapy).
Other: extremely rare - allergic reactions.
Contraindications to the drug:
Hypersensitivity to the components of the drug.
Use during pregnancy and lactation.
It is possible to use Terzhinan during pregnancy and lactation ( breastfeeding) according to indications.
Special instructions for the use of Terzhinan.
It is necessary to conduct simultaneous treatment of the sexual partner because of the risk of re-infection.
Drug overdose:
Due to the low degree of absorption into the systemic circulation, overdose is unlikely.
Interaction of Terzhinan with other drugs.
clinically significant drug interaction the drug Terzhinan with other drugs has not been identified.
Conditions of sale in pharmacies.
The drug is dispensed by prescription.
Terms of the storage conditions of the drug Terzhinan.
The drug should be stored at room temperature. Shelf life - 3 years.
In this article, you can read the instructions for use medicinal product Terzhinan. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Terzhinan in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Terzhinan in the presence of existing structural analogues. Use for the treatment of thrush (candidiasis), vaginitis, vaginosis, trichomoniasis and other infectious diseases of the female genital area, including during pregnancy and lactation. Menstruation and discharge while taking the drug. Can I have sex while taking medication.
Terzhinan- combined preparation for local use in gynecology. The action of the drug is due to the properties of its constituent components.
The composition and action of the components of the drug
Ternidazole - an imidazole derivative - has a trichomonacid effect, is also active against anaerobic bacteria, in particular Gardnerella spp.
Neomycin sulfate is a broad-spectrum antibiotic from the group of aminoglycosides.
Nystatin is an antifungal antibiotic from the group of polyenes, highly active against fungi of the genus Candida.
Prednisolone is a glucocorticoid that has a pronounced anti-inflammatory effect.
The composition of the excipient ensures the integrity of the vaginal mucosa and the constancy of pH.
Pharmacokinetics
Studies of the pharmacokinetics of the drug Terzhinan were not conducted due to low systemic absorption.
Indications
Treatment of vaginitis caused by microorganisms sensitive to the drug:
- bacterial vaginosis;
- bacterial vaginitis caused by banal pyogenic or conditionally pathogenic rod microflora;
- trichomoniasis of the vagina;
- vaginitis caused by fungi of the genus Candida;
- mixed vaginitis.
Prevention of vaginitis:
- before gynecological operations;
- before childbirth or abortion;
- before and after the installation of the IUD;
- before and after diathermocoagulation of the cervix;
- before hysterography.
Release form
Vaginal tablets, in packs of 6 and 10 tablets (sometimes erroneously called vaginal suppositories).
Instructions for use and dosing regimen
Assign 1 vaginal tablet (candle) per day before bedtime. The average duration of the course of therapy is 10 days; in case of confirmed mycosis, it can be increased up to 20 days. Do not stop treatment during menstruation.
Before insertion into the vagina, the tablet should be held in water for 20-30 seconds.
Side effect
- burning sensation;
- local irritation (especially at the beginning of therapy);
- allergic reactions.
Allocations when using the drug are not typical, you should contact your doctor for advice.
Contraindications
- hypersensitivity to the components of the drug.
Use during pregnancy and lactation
It is possible to use Terzhinan during pregnancy and lactation (breastfeeding) according to indications.
special instructions
It is necessary to conduct simultaneous treatment of the sexual partner because of the risk of re-infection. Also, at the time of treatment with Terzhinan, sexual contacts (sex) with a partner should be excluded.
drug interaction
No clinically significant drug interactions of Terzhinan with other drugs have been identified.
Analogues of the drug Terzhinan
Terzhinan has no structural analogues for the active substance.
In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.
Content
The drug Terzhinan during pregnancy is taken in the form of suppositories inserted into the vagina for the treatment of diseases caused by the reproduction of pathogenic and opportunistic microorganisms. In 70% of women who are expecting a baby, the optimal balance of the microflora of the genital organs occurs in the body due to changes in the functioning of the hormonal, immune and digestive systems. Terzhinan is prescribed to pregnant women not only for treatment, but also for the prevention of this pathology.
What is Terzhinan
When carrying a child, women often develop diseases of a bacterial and fungal nature - vaginitis, candidiasis, latent sexually transmitted infections. Candles Terzhinan during pregnancy is used to eliminate the unpleasant symptoms of the disease on the mucous membrane of the genital organs and inhibition of pathogenic microbes. This combined remedy effectively treats and prevents the development of inflammatory processes.
Active substance
The therapeutic effect of the drug is associated with the content of the components that make up its composition - such as:
- Ternidazole is a substance with antibacterial activity. It is most effective against Trichomonas.
- Nystatin is an antifungal component that fights candidiasis.
- Neomycin - this substance belongs to the group of aminoglycoside antibiotics that treat purulent complications infectious infection.
- Prednisolone is a corticosteroid that stops the development of inflammation processes.
Terzhinan - hormonal or not
The composition of the drug includes four active ingredients, one of which belongs to the group of corticosteroids. Prednisolone is a glucocorticoid that quickly reduces local inflammation of the vaginal mucosa, itching, burning. The dose of the content of this substance is small - 3 mg per 1 tablet. Terzhinan is classified as a hormonal drug, so its use is prohibited without the permission of a doctor.
Why is it prescribed to women
Vaginal suppositories and the pills are safe when taken properly. This remedy is prescribed to ordinary patients and women expecting a baby. Treatment can be carried out during the period of menstruation. Terzhinan is prescribed for several conditions of the body and for the treatment of such infectious pathologies as:
- colpitis;
- vaginitis;
- purulent discharge from the birth canal;
- prevention of infection due to surgery;
- the recovery period after the treatment of cervical erosion or the installation of a contraceptive spiral;
- preparation for surgery and childbirth;
- after suturing the cervix due to isthmic-cervical insufficiency;
- to prevent the development of inflammation while wearing an unloading obstetric pessary;
- genital ureaplasmosis;
- trichomonas;
- gardnerellosis;
- candidiasis;
- inflammation of the appendages.
Can it be used during pregnancy
Women in position should receive treatment under the supervision of a specialist. The doctor makes an assessment of the patient's condition during a periodic examination and according to the results of laboratory tests. Terzhinan for thrush during pregnancy and for the treatment of other infectious diseases of the genital organs is prescribed according to the same system as for women who are not expecting a baby. Possessing local action, the drug practically does not penetrate into the blood, so it is not considered dangerous for the fetus, but only in the later stages of gestation.
Terzhinan in early pregnancy
At vaginal application Terzhinan during pregnancy active ingredients enter the bloodstream in small quantities. In the first three months of bearing a child, it is strictly forbidden to use the drug. This is a period of active formation internal organs and systems of the baby's body, and the components that the medicine contains can cause congenital pathologies. To suppress infections in the first trimester, it is recommended to use more gentle means.
In the 2nd trimester
For pregnant women in the second trimester, prohibitions are lifted that limit the use of a number of medications, but antibiotics are not included in this list. Terzhinan contains components that inhibit the activity of microorganisms, but it is approved for use. The drug is available in the form vaginal tablets, so the amount of substances that can penetrate the blood will be small and at this stage of the baby's development they will not cause harm.
In the 3rd trimester
Terzhinan and pregnancy in the third trimester are compatible. This is very effective drug used for the treatment and prevention of infectious inflammation. To the indications for the appointment of Terzhinan during pregnancy for long periods, the treatment of the birth canal is added immediately before the appearance of the child in order to protect the baby from infection during the birth of the baby.
How Terzhinan works
The drug Terzhinan during pregnancy is highly active against a number of pathogens: trichomonas, gardnerella, fungi and other bacteria. Local application The drug protects the epithelial cells of the mucous membranes of the genital organs and maintains the physiological acid-base balance of the internal environment of the vagina. Terzhinan, used during pregnancy, maintains the optimal ratio of beneficial bacteria with opportunistic pathogens living on the genitals.
Prednisolone, which is part of the drug, reduces the manifestation of local allergies, the amount of exudate, and inflammation. Ternidazole inhibits the reproduction of protozoa (Trichomonas) and some anaerobic bacteria. Neomycin kills staphylococci, E. coli, streptococci, shigella. Nystatin effectively fights the fungus. Microorganisms slowly develop resistance to Terzhinan.
Instructions for use during pregnancy
Ratio active substances the drug is chosen so as to cause a synergistic, mutually reinforcing effect on pathogenic microbes, without affecting the natural microflora of the vagina. The medicine is released in the form of yellow vaginal tablets / suppositories. The active ingredients in its composition are contained in the following quantities:
- prednisolone - 3 mg;
- ternidazole - 200 mg;
- neomycin sulfate - 100 mg;
- nystatin - 100 thousand IU.
It is advisable to take Terzhinan immediately after menstruation, but menstruation is not considered a contraindication to the use of the drug. To prevent re-infection with pathogens, the sexual partner must also undergo treatment. The tool is allowed to be used not only by pregnant women, but also by lactating women, because it does not penetrate into breast milk. In addition, it was noted that the drug does not affect the reaction rate.
How to enter
The use of Terzhinan, like other medicines, has certain features. Candles are inserted into the vagina, following simple recommendations:
- Before the introduction, tear the shell of the drug, place it in boiled water at room temperature for 30 seconds.
- Insert a wet suppository / tablet deep into the vaginal cavity, lying on your back, bending your knees.
- After placing the medicine in the birth canal, lie down for 15-30 minutes.
- It is better to inject the tablet at bedtime and not get up after that, so that the melted drug does not leak out when you get up.
- If menstruation starts, then continue the course of treatment.
Dosage
The drug does not affect the effectiveness of drugs taken orally, because the dose of active components that have penetrated into the blood is small. Terzhinan during pregnancy is taken intravaginally, one capsule per day. The drug should be injected deep into the vagina, preferably at bedtime. The course of treatment should not exceed 10 days. According to the decision of the attending physician in case of complicated vaginitis, the drug is prescribed to be taken for 3 weeks. For preventive purposes, the drug should not be used for more than 6 days.
Side effects of Terzhinan
Only the attending physician can prescribe the drug, because sometimes Terzhinan can cause side effects. In most cases, such a reaction is observed in the first days of treatment. Patients feel itching, burning, but gradually all the unpleasant symptoms disappear. Nuances:
- If the side effect of the drug increases, then you should contact a specialist to replace Terzhinan with a similar drug.
- Candles act locally, so an overdose is almost impossible.
- To avoid possible complications follow the doctor's recommendations.
Allocations after Terzhinan during pregnancy
Sometimes, when taking the drug, a woman may be frightened when she sees vaginal discharge. In such a situation, you need to decide why this is happening. Terzhinan is well tolerated during pregnancy, so the main reason for the appearance of liquid is the melting of the substance that makes up the candle. The vaginal mucosa absorbs only part of the active ingredients, the rest flows out. The liquid preparation can leave the vagina for several hours. These secretions are not considered pathological. In order not to stain the linen, use sanitary pads during the treatment period.
Burning from Terzhinan
At the beginning of treatment with Terzhinan's suppositories, the vaginal mucosa may burn slightly and itching can be observed. After two or three days, such unpleasant phenomena should completely disappear against the background of a decrease in the inflammatory process. If the patient has an individual intolerance to any component of the drug, then the listed symptoms will intensify. In this case, she needs to urgently seek help from a doctor, and stop taking the prescribed remedy.
Contraindications
Terzhinan during pregnancy is absolutely contraindicated in the first trimester. During this period, the formation and development of the fetus occurs, and the drug contains active ingredients, even small doses of which can cause significant harm to the child. In severe conditions, when the expected benefit to the mother outweighs the possible risks to the child, the decision to prescribe the drug should be made by the doctor.
In addition, contraindications for the use of the drug include individual intolerance to the individual components that make up its composition, and allergic reactions. Most cases of burning sensation after taking the drug do not require discontinuation of the drug. This feeling goes away in a few hours. If unpleasant symptoms intensify and mucosal edema develops, then you need to take some kind of allergy remedy, and do not administer suppositories anymore.
Price Terzhinan
Prices for this drug practically do not differ in different cities. Vaginal tablets, manufacturer - Bouchard laboratory, France, package No. 6 cost from 336 to 363 rubles, No. 10 - 435-466 rubles. In addition, it is possible to purchase a medicine in an online pharmacy. Purchases can be received by mail or choose delivery to the addressee by courier company.
Candles Terzhinan are a combined preparation, which is characterized by the presence of antifungal and bactericidal properties.
Many users ask what Terzhinan candles are, what they help with.
With the help of this medication, you can get rid of anaerobic microorganisms, pyogenic bacteria, fungi, etc.
Due to the presence of a substance called ternidazole in the composition of this drug, it is used to produce a high-quality fight against Trichomonas. When using the drug, anaerobic microorganisms also die.
The destruction of protein synthesis in the cells of pathogenic microorganisms is carried out with the help of neomycin. This also contributes to the fact that the transcription of the genetic code is disrupted.
As a result, microbial cells die. Some people have a question, what are Terzhinan candles made of, what are they from? Given medication fully fights corynebacteria, Staphylococcus aureus, methicillin, listeria. All these microorganisms belong to the category of anaerobic bacteria.
As a result of the study of suppositories, the sensitivity of gram-negative bacteria to it was noticed. Pseudomonas aeruginosa is one of the bacteria that this medication destroys.
Terzhinan is characterized by the presence in its composition of nystatin, which is an antimycotic agent. That is why when using the drug, binding of nystatin and ergosterol, which is a component of the fungal cell membrane, is observed.
This leads to damage to the shell and to the death of fungi.
Sensitivity to this drug is also shown by fungi that belong to the category of the genus. With the help of Terjignan, you can fully fight against eukaryotes.
Some patients have a question, one hundred such candles Terzhinan, from what they are prescribed? Due to the presence of prenisolone in the preparation, it is characterized by the presence of anti-allergic, anti-inflammatory and anti-exudative action.
During the reception of this drug, there is no damage to the vaginal tissue of the epithelium. The pharmacokinetics of the drug has not been studied. This is due to the fact that Terzhinan has a low systemic absorption.
Candles Terzhinan are characterized by very good absorption, which allows them to be fully used for the treatment of various fungal and bacterial infectious diseases. More about Terzhinan will tell on the video:
Reasons for using Terzhinan
Thanks to unique composition of this medication, with its help, the fight against various diseases external genitalia of the female representatives, which are characterized by an infectious nature.
This medication is prescribed to patients in the presence of vaginitis, which occurs as a result of exposure to pyogenic microflora. Also, this drug is prescribed by doctors for recurrent colpitis, which belongs to the category of non-specific vaginitis.
With trichomonas vaginitis and vaginal dysbiosis, Terzhinan is also prescribed. If, as a result of the activity of fungi of the genus Candida, a female representative has vaginitis, then taking this medication is recommended by doctors.
With vaginitis, which have a mixed nature of origin, Terzhinan can also be used.
The drug is a prophylactic that is widely used to prevent the appearance of female representatives, who will later undergo various surgical interventions.
This medication is most often taken before the process of childbirth, abortion. If the patient is prescribed diathermocoagulation, then she needs to use suppositories not only before the procedure, but also after it.
Before conducting such a study as metrosalpinography, this drug is also used.
Terzhinan is used if the patient will be administered intrauterine. This medication in this case is used not only before the procedure, but also after it. With complications antibiotic therapy candles may also be used.
Candles Terzhinan are a broad-spectrum drug, which allows them to be used to treat various diseases.
Features of taking the drug
This medication is used when patients have:
- Vaganitov
- Vulvovaginitis
- , which are characterized by non-specific origin.
In order to prevent infections before operations, childbirth, candles are also used. Terzhinal is characterized by a high level of effectiveness and therefore it is widely used for preventive purposes.
Taking the drug is quite simple. Candles must be inserted into the vagina after taking hygiene procedures. This drug is taken for 10 days. At a time, a female representative must be inserted into the vagina one candle at a time.
In order for the suppository to soak, it is soaked in water for one minute before insertion into the vagina. After that, it should dry out a little.
When using this medication for the treatment of thrush, they must be used within 20 days. At the end of taking suppositories after three days, the patient must re-test, with which the doctor can determine the effectiveness of the treatment.
The course of taking Te5rzhinan suppositories is determined depending on the type of disease and the individual characteristics of the female representative.
Treatment of any disease with the help of this medication should not be done independently, as this can lead to disastrous consequences. In this case, you must first consult a specialist.
Possibility of side effects and contraindications of Terzhinan
Like any other drug, this drug is characterized by the presence of actions. They happen on very rare occasions. The introduction of this drug is carried out locally.
That is why the absorption of the drug is carried out in the systemic circulation in a very low concentration.
In registered cases side effects Terzhinan observed the presence of allergic symptoms in the vaginal area and external genitalia. In some cases, female representatives complained of a burning sensation during the use of this drug.
Also, during use, tingling may be observed. Discomfort for women during the use of the drug brings itching. During the use of suppositories, female representatives experienced irritation in the pelvic area.
A very rare side effect while taking this medication is poor wound healing. Atrophy of the mucous membranes of the vagina was observed in isolated cases of taking this medication.
To ensure that during the reception of this medication does not occur side effects should not be taken in the presence of pronounced contraindications.
Terzhinan is forbidden to be taken by women who have pronounced allergic reactions.
The use of the drug is carried out by female representatives, whose age is more than 16 years.
Terzhinan is a universal drug that is widely used to treat diseases in women. The drug is characterized by ease of use and high impact.
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