Maalox suspension - instructions for use. How long can I take Maalox Does Maalox help?

Maalox (Maalox) is an antacid drug that has an adsorbing and enveloping effect, due to which the impact of damaging factors on the mucous membrane of the esophagus and stomach is reduced. These mechanisms protect the mucosa from damage by chemically aggressive components.

Composition and form of release

Maalox is tradename a popular combination drug based on hydroxides: magnesium and aluminum, the latter is called algeldrate. Composition of one sachet of suspension (15 ml). Active substances:

• Magnesium hydroxide 600 mg
• Aluminum hydroxide 525 mg
• Excipients:
• Concentrated hydrochloric acid 0.018 ml
• Citric Acid Monohydrate (E33O) 9.82 mg
• Peppermint essential oil 1.89 mg
• Mannitol (E421) 37.50 mg
• Methyl parahydroxybenzoate (E218) 15.00 mg
• Propyl parahydroxybenzoate (E216) 7.50 mg
• Sodium saccharinate (E954) 4.215 mg
• Sorbitol 70% (non-crystallizing) (E420) 214.3 mg
• Hydrogen peroxide 30% (9.75 mg)
• Purified water up to 15 ml.

pharmachologic effect

The therapeutic effects and action of Maalox are due to its constituent magnesium hydroxide and aluminum hydroxide. A mixture of these components is commonly referred to as aluminum magnesium hydroxide (AMH). So, AMG has the following therapeutic effects:

• Antacid;
• Adsorbing;
• Enveloping.

The drug neutralizes free hydrochloric acid without causing secondary hypersecretion of hydrochloric acid. Due to the increase in pH when it is taken, the peptic activity of gastric juice decreases. It also has an adsorbing and enveloping effect, due to which the impact of damaging factors on the mucous membrane is reduced.

Indications

What helps Maalox and its substitutes? Both Maalox and most of the drugs that replace it have a large number of positive therapeutic effects:

• adsorbent;
• enveloping;
• choleretic;
• antacid.

A big plus of this remedy is that it is practically not absorbed into the blood, and, therefore, it has an exclusively local effect.

The instructions for the drug indicate that the indication for the use of Maalox is:

• peptic ulcer and duodenum in the acute phase;
• acute or chronic gastroduodenitis, with normal or increased secretory function in the acute phase;
• , reflux esophagitis;
• dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching after errors in the diet, excessive consumption of ethanol, coffee, nicotine
• dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, acid belching (and their prevention), resulting from the use of certain drugs (NSAIDs, GCS).

Maalox may also be administered to patients as part of complex therapy with dyspepsia, accompanied by putrefactive processes in the intestines, sluggish motility, stagnant processes in the gallbladder.

Instructions for use

Tablets must be sucked or chewed thoroughly in the mouth, and only then swallowed. If saliva is produced a little, then after chewing or resorption, you can drink the pill with a few sips of clean non-carbonated water.

How to take the drug? Maalox usually accepted 1-1.5 hours after eating or when pain occurs.

Maalox tablets and suspension are intended for the treatment of patients in over 15 years of age.

Maalox tablets

Tablets: taken orally, chewing thoroughly. Recommended dosage: 1-2 tablets 3-4 times a day 1-2 hours after meals and at bedtime. When the break between meals and taking pills should be shortened. The course of treatment is no more than 2-3 months. For episodic use, a single dose of 1-2 tablets is indicated.

Maalox in suspension

Suspension: in the form of a suspension, take 15 ml (1 package). Before use, homogenize the suspension by carefully kneading the bag between the fingers. Squeeze the contents of the package into a spoon or mouth.

How to take Maalox with errors in the diet? Usually course treatment is not required, 1 sachet or 15 ml of the product is enough. As a preventive measure, it is enough to drink 5-10 ml of the suspension before meals. In the form of tablets, 2-3 tablets are required per dose. The dose may be increased to 3-4 tablets if necessary.

It is important to say that the nuances of taking this remedy should be discussed with the attending physician, who individually approaches each patient and a separate clinical case.

Contraindications

• Increased individual sensitivity to the components of the drug;
• Chronic renal failure;
• Age of children under 12 due to lack of clinical trials;
• Pregnancy period in the 1st trimester;
• Alzheimer's disease;
• Hypophosphatemia.

The instructions for Maalox indicate that: it is necessary to use the drug with caution in patients on hemodialysis with porphyria, during pregnancy, Alzheimer's disease, with diabetes(tablets for chewing).

Application during pregnancy

The instructions for the drug say that during the period of bearing a child, Maalox can be taken only in extreme cases. Sufficient studies that would confirm the safety of taking the drug have not been conducted, so the manufacturer recommends using it only in cases where a woman's health is more important than the risk of developing possible pathologies at the fetus.

When using the drug in accordance with the dosing regimen, the absorption of combinations of aluminum hydroxide and magnesium salts in the mother's body is limited, therefore Maalox is recognized as compatible with breastfeeding.

Before use, be sure to consult your doctor.

special instruction

The patient should contact their doctor if:

• weight loss;
• difficulty in swallowing;
• digestive disorders that appeared for the first time, changes in existing digestive disorders;
• kidney failure.

It is also important to take into account that when long-term treatment Maalox the patient's diet should include a sufficient amount of phosphates, since one of the active ingredients of the drug (algeldrate) can lower the level of phosphorus in the body.

Side effects for the body

• Constipation;
• Lack of appetite;
• Feeling of fullness and heaviness in the epigastric region;
• Nausea, vomiting.

Overdose

An overdose of Maalox suspension or tablets is manifested by the following symptoms:

• Diarrhea;
• Abdominal pain;
• Narrowing of the intestinal lumen;
• Vomit;
• encephalopathy;
• Phosphorus deficiency.

Interaction with other drugs

A 2-hour interval should be observed between the use of Maalox and other drugs.

Shelf life of tablets and suspensions

Store Maalox in a dark and dry place at room temperature. Keep away from children in a closed place.

• The shelf life of the suspension in sachets is 3 years, in vials - 30 months.
• Shelf life after the first opening of the vial is 6 months.

Analogues

Analogues of the drug Maalox are:

• gastracid tablets;
• Maalukol;
• Alumag tablets;
• Almagel suspension;
• Gaviscon suspension and tablets.

Prices in pharmacies

The cost of various forms of Maalox in pharmacies varies within the following limits:

• Maalox tablets - about 230 rubles;
• Blue sachets 4.3 ml, pack of 6 - 160 rubles;
• Suspension, 15 ml, 30 pcs. - the price is about 780 rubles;
• Suspension, 250 ml bottle - 450-500 rubles.

Maalox is a combined drug that has a beneficial effect on the stomach and esophagus and has antacid, enveloping, adsorbing, choleretic and carminative effects.

Release form and composition of Maalox

Maalox is available as chewable tablets, suspension in vials and sachets.

The main active ingredients of Maalox are: aluminum hydroxide and magnesium hydroxide.

One chewable tablet contains 400 mg of the main active ingredients. The excipients are: sucrose, mannitol, sorbitol, starch, magnesium stearate, sodium saccharinate and mint flavor.

100 ml of Maalox suspension contains 3.5 g of aluminum hydroxide and 4 g of magnesium hydroxide. The excipients are: citric acid monohydrate, concentrated hydrochloric acid, essential oil mint, methyl parahydroxybenzoate, mannitol, sodium saccharinate, propyl parahydroxybenzoate, non-crystalline sorbitol, hydrogen peroxide and purified water.

1 sachet of Maalox suspension contains 525 mg of aluminum hydroxide and 600 mg of magnesium hydroxide.

Suspension Maalox is more effective tool because it is made up of smaller particles.

Pre-resorbed or chewed tablets have a greater acid-neutralizing effect than tablets swallowed whole.

Pharmacological action of Maalox

The action of the drug is based on the neutralization of free hydrochloric acid, which results in a decrease in the peptic activity of gastric juice. Maalox has an enveloping and adsorbing effect, protecting the mucosa of the gastrointestinal tract from the influence of damaging factors.

The drug does not cause secondary hypersecretion of gastric juice and reduces pain in the upper parts of the digestive system for several hours.

Indications for use Maalox

Maalox is prescribed for:

• exacerbation peptic ulcer stomach and duodenum;
• reflux esophagitis, hiatal hernia;
• exacerbation of acute and chronic gastroduodenitis with increased or normal secretory function;
• discomfort or pain in the epigastric region, heartburn, acid eructation after an error in the diet, excessive consumption of coffee, nicotine, ethyl alcohol;
• discomfort or pain in the epigastric region, heartburn, acid belching after the use of certain drugs (NSAIDs, glucocorticosteroids, and others);

as well as for the prevention of erosive and ulcerative lesions of the gastrointestinal tract during long-term therapy with NSAIDs and glucocorticoids.

Contraindications to the use of Maalox

You should not take Maalox:

• with severe renal failure;
• with hypophosphatemia;
• with increased sensitivity to the components that make up the drug;
• in case of isomaltose / sucrose deficiency, fructose intolerance and glucose-galactose malabsorption;
• under the age of 15 years.

Maalox should be taken with caution:

• patients with porphyria who are on hemodialysis;
• with Alzheimer's disease;
• in case of impaired renal function (in such patients, when taking the drug, an increase in the concentration of aluminum and magnesium is possible, with prolonged use of Maalox in high doses, dementia, encephalopathy and microcytic anemia may develop);
• during pregnancy and lactation;
• with a low content of phosphates in food (to avoid the development of phosphate deficiency).

How to use Maalox and dosage

According to the instructions, Maalox is taken orally.

Tablets must be sucked or chewed well.

The drug is prescribed one or two tablets 3-4 times a day an hour or two after meals, and also at night. The maximum allowable number of pills is 6 times a day. Do not take more than 12 tablets per day.

Maalox suspension is taken when pain occurs or 1-2 hours after a meal. Usually prescribed 1 tablespoon or 1 sachet (15 ml) 3-4 times a day (but not more than 6 sachets per day, a break between doses of at least 2 hours). Before use, shake the bottle with the suspension, and knead the sachet between the fingers. The contents of the sachet are squeezed directly into the mouth or into a spoon.

In the case of reflux esophagitis, Maalox is taken some time after a meal.

The course of treatment with Maalox should not exceed 2-3 months.

In the case of episodic use, Maalox is taken once, 1-2 tablets or 1 tablespoon (15 ml).

Side effects of Maalox

According to the instructions, Maalox, if the dosage regimen is observed, does not cause side effects or they are insignificant.

Sometimes there are: constipation, diarrhea, vomiting, nausea, changes in taste sensations.

In rare cases, with prolonged use of large doses of the drug by patients with renal insufficiency, they may develop dementia, encephalopathy, microcytic anemia.

In patients with concomitant renal insufficiency, plasma concentrations of aluminum and / or magnesium may increase, blood pressure may decrease, thirst and hyporeflexia may develop.

With prolonged use of the drug in high doses (especially with a lack of phosphates from food), hypophosphatemia, hypocalcemia, hypercalciuria, osteoporosis, nephrocalcinosis, osteomalacia may occur.

The use of Maalox during pregnancy and lactation

Currently, no teratogenic effects have been identified when using Maalox during pregnancy, but due to the fact that clinical experience is not yet sufficient, the use of Maalox during pregnancy is possible only after consulting a doctor.

Prescribing Maalox during pregnancy in high dosages for a long time should be avoided.

When taking Maalox, it is not necessary to stop breastfeeding.

Interaction of Maalox with other drugs

While taking Maalox with antibiotics, the absorption of ciprofloxacin, digoxin, tetracycline antibiotics, ofloxacin, indomethacin decreases.

Maalox also reduces the absorption of acetylsalicylic acid, beta-blockers, histamine H 2 receptor blockers, diflunisal, chlorpromazine, phenytoin, isoniazid, phosphorus-containing drugs.

When using the drug together with quinidine, serum concentrations of quinidine increase, an overdose of quinidine may develop.

Special instructions for the use of Maalox

It is necessary to observe a 2-hour break between taking Maalox and other drugs and a 4-hour break between taking Maalox and fluoroquinolones.

Long-term use of the drug in case of impaired renal function should be avoided.

With prolonged use of the drug, it is necessary to monitor the sufficient intake of phosphates in the body.

Patients with diabetes should take into account that the drug contains sucrose.

Maalox storage conditions

According to the instructions, Maalox should be stored at a temperature not exceeding 25ºС.

For any drug, including such as Maalox, the instruction for the use of the drug was created so that a person can find out if he needs this drug and whether it can be used in a particular case. This article is written in order to acquaint the reader with what kind of tool it is, what its purpose is, and what are the basic rules for use.

If you are looking for Maalox - instructions for use, price, reviews, analogues, this means that you do not know secondhand what heartburn is and pain in the stomach, and probably an ulcerative lesion of the gastrointestinal tract.

General description of the drug

Maalox is the trade name for a popular combined drug based on hydroxides: magnesium and aluminum, the latter is called algeldrate. Maalox is labeled as an antacid. That is, a drug that can neutralize the acid of the juice produced by the stomach. Magnesium in the form of hydroxide is intended to have an effect that softens the effect of algeldrate. Unfortunately, for such a tool as Maalox, the price will not please the buyer. Like most antacids, this remedy costs more than 100 rubles (suspension) and more than 200 rubles (tablets).

Maalox instructions for use describe how a remedy that can not only bind free hydrochloric acid in the stomach, but also does not cause its repeated excessive secretion. When describing the drug Maalox, the instruction states that it is able to adsorb excess gastric juice and envelop the walls of the organ. This is what allows you to minimize the impact of factors that damage the walls of the stomach, as well as the esophagus. The drug is practically not absorbed in the stomach, due to this, the systemic effect on the body with the correct intake of the drug is practically not observed.

The medicine is produced in two forms:

1. Maalox suspension;
2. Maalox tablets.

Tablets have an antacid effect, have an enveloping, choleretic and some carminative effect. Maalox tablets are made in a chewable form.

When describing Maalox, the instructions for the use of tablets and suspensions warn that you should consult a doctor before taking the drug. Since the drug affects the absorption of other medicines, including antibiotics (tetracyclines, quinols and a number of others), beta-blockers (propranolol), drugs (Digoxin), anti-inflammatory drugs, including salicylates, and some other drugs.

Maalox: instructions for use (official)

When should the remedy be used?

For Maalox, the indications for use are rather limited. This inflammatory diseases GIT. Most often, diseases are associated with an increase in the acidity of the juice produced by the stomach. Less commonly, the drug is required for normocidal inflammation. First of all, these are gastritis and gastroduodenitis, ulcerative lesions of the gastrointestinal mucosa of various etiologies, hernia in the esophagus and exophageal reflux.

Maalox tablets are recommended for use in case of pancreatic pathology (acute pancreatitis or chronic course of the disease in the acute stage), with heartburn after the abuse of fatty and fried foods, coffee drinks and alcohol. Maalox suspension instructions for use suggest using in case of dyspeptic phenomena:

• medication;
• fermentation;
• putrid.

Drug indigestion can develop after long-term use hormonal drugs, NSAIDs and some other drug groups. In some cases, Maalox suspension is recommended for use as a preventive measure in the complex treatment of various diseases in order to neutralize the effect of agents that irritate the gastrointestinal mucosa.

Briefly answering the question of Maalox from what? We can say that this remedy is designed to prevent the formation of stomach and duodenal ulcers, help eliminate inflammation of the gastrointestinal mucosa and remove such a symptom as heartburn.

Main contraindications and side effects

Like any drug, Maalox should be used as prescribed by a doctor, taking into account your state of health, age and possible pregnancy (for women).

When should you not take the remedy?

Maalox during pregnancy is categorically not recommended, and has limited use in breastfeeding for a nursing mother. To date, the teratogenic effect of the drug has not been confirmed, but due to the fact that insufficient clinical trials have been carried out, in the case of pregnancy and lactation, it is better to replace this remedy with a safer one.

Maalox - instructions for use of the suspension and tablets do not recommend offering this antacid to children under 15 years of age (suspension), up to 12 years of age (tablets), persons suffering from chronic renal failure (renal failure in chronic form) and hypophosphatemia. Due to the fact that the drug contains sorbitol, it should not be used by people with sucrase deficiency. If any of the components of the drug causes allergic reaction, the tool cannot be used.

How is Maalox taken for porphyria, dietary phosphate deficiency, or senile Alzhelmer's dementia? Very carefully and under the strict supervision of the attending physician. With chronic renal failure, the remedy, if taken for a long time and uncontrollably or in large doses, leads to (headaches), anemia and dementia (weakening of cognitive activity, that is, acquired dementia).

Side effect

Prolonged use of the drug, or high doses, lead to indigestion, which manifests itself in the form of constipation or diarrhea, nausea and even vomiting. With constant use, the work of taste buds is disrupted. Disorders in the skeletal system (osteoporosis and osteomalacia) may develop. Patients with CRF develop hypotension, thirst, and hyperreflexia. And other changes in the body.

Rules for the use of Maalox

The suspension is available in sachets, before drinking the contents, the sachet must be kneaded with your fingers to bring the contents into a homogeneous state. The suspension is drunk in its original form, it is not diluted with water. The maximum daily dose of the drug is 90 ml, which corresponds to 6 sachets. For Maalox, the application, or rather the method of application, is very simple. It is recommended to take 1 sachet 30 minutes before meals for stomach ulcers and 1-2 hours before meals in other cases. With a strong, it is recommended to take the drug at night, and at the time of the burning sensation.

How to take Maalox with errors in the diet? Usually course treatment is not required, 1 sachet or 15 ml of the product is enough. As a preventive measure, it is enough to drink 5-10 ml of the suspension before meals. In the form of tablets, 2-3 tablets are required per dose. The dose may be increased to 3-4 tablets if necessary.

For Maalox, its use for prevention is recommended in the amount of 1-2 chewable tablets. Tablets must be chewed, not swallowed. The course treatment with Maalox, the instructions for use, suggests that it be carried out no longer than 3 months in a row.

The price of the drug and its analogues

Does the described drug have analogues? Of course, since Maalox is just a trade name. For the drug Maalox analogues are available in different forms. For example, there are Maalukol chewable tablets, you can buy Gastacid resorption tablets. In the form of a gel for use per os (through the mouth), Palmagel is available. There are a lot of products on the market in the form of suspensions, Gastacid, Or Altacid. Or in a simple tablet form - Alumag and Ajiflux.

If the reader is interested in Maalox instructions for use, the price of the drug will also interest him. It's not the best cheap drug like all antacids. Can be found:

• Maalox tablets at a price of 250 rubles for 20 pcs;
• Maalox suspension at a price of 150 rubles (price for 30 sachets);

For Maalox, the price of a suspension (one sachet) will be about 23 rubles. Maalaox is not the cheapest antacid. There are no very cheap products in this group, but, nevertheless, you can choose more economical products. So, for the drug Maalox - the prices of cheap analogues, at least more socially adapted ones, will be about 120-130 rubles. For the Maalox brand drug, analogues are cheaper - these are, first of all, Ajiflux (about 130 rubles) and Gastrocid (from 60 to 120 rubles).

For Maalox, the price of tablets and suspensions can reach 600 rubles. It depends on the quantity in the package. This is the main disadvantage of the drug in its group. In other respects, it is no different from its more economical counterparts.

If the drug is used according to its intended purpose, and not for spastic pains or other problems that the remedy cannot solve, reviews on Maalox are most often positive. Heartburn and discomfort in the stomach, the drug eliminates well. The main negative is the price of funds. Some people don't like the taste (mint with a slight metallic taste), but those who enjoy chewing mints will not mind chewing a mint antacid tablet.

This is brief information that will help the reader decide what Maalox is, the price, instructions for using the drug, and how it can be replaced if necessary.

Video: Good dad. Medicines for and (Dr. Komarovsky)

The drug Maalox belongs to the group of antacids, which are prescribed to patients for the treatment and prevention of gastrointestinal diseases.

Maalox tablets have a fast therapeutic effect. The medicine helps in the fight against heartburn and pain in the gastrointestinal tract. Because medication protects the gastric mucosa from damage, it begins to regenerate faster. Statistics clinical research shows that, subject to the instructions for use, the drug is easily tolerated, adverse reactions rarely occur.

The drug Maalox, which is part of the antacid group, is a complex drug. The composition of the drug includes Algeldrat, which has a systemic effect on the digestive tract:

• adsorbs;
• envelops;
• has a choleretic effect.

The composition of Maalox tablets includes magnesium hydroxide, which has a mild laxative effect. This substance helps to eliminate excessive gas formation, and the process of fecal discharge gradually normalizes.

The antacid helps to normalize the acidity of the stomach, as the activity of hydrochloric acid and gastric juice decreases.

Composition of Maalox

Each tablet of the drug contains 400 mg of Algeldrate (aluminum hydroxide), as well as some auxiliary components, including magnesium hydroxide.

Release form and packaging

The drug can be produced in the form of a suspension in bags or vials, as well as in tablet form.

Maalox suspension, produced in sachets (15 ml), contains 525 mg of aluminum hydroxide and 600 mg of magnesium hydroxide.

Suspension in vials (100 ml per vial) contains 3.5 gr. and 4 gr. active ingredient, respectively.

The tablet form contains 400 mg of magnesium hydroxide and aluminum hydroxide. The package may contain from one to four blisters of 10 tablets each.

Maalox is available without a prescription.

Pharmacological actions

The mechanism of action of Maalox is based on the neutralization of free hydrochloric acid, which is part of the gastric juice, while acid secretion does not increase. After the drug enters the digestive organ, the pH value increases, so the gastric juice becomes less aggressive.

The substances that make up Maalox envelop the gastric mucosa and have an adsorbing effect. The mucosa is protected from the damaging effects of aggressive chemical components.

The drug has a local effect, is practically not absorbed into the blood, which means that it does not have another therapeutic effect on the body. Excreted naturally with feces.

Indications for use Maalox

Maalox tablets and suspensions are prescribed to patients with the following pathological processes in the body:

• acute inflammation of the gastric mucosa;
• increased acidity of gastric juice;
• exacerbation of stomach and duodenal ulcers;
• pain in the upper gastrointestinal tract, accompanied by sour belching;
• heartburn;
• erosion of the mucous membranes of the gastrointestinal tract;
• hyperphosphatemia;
• hernia of the esophagus (diaphragmatic);
• inflammatory process in the pancreas in the acute phase;
• with reflux esophagitis;
• pain in the epigastrium caused by malnutrition, alcohol abuse and taking certain medications.

In addition, the drug can be prescribed to some patients as part of complex treatment dyspepsia, accompanied by impaired motility, putrefactive processes in the gastrointestinal tract, as well as stagnation in the gallbladder.

With reflux - esophagitis, Maalox is prescribed

Maalox is also prescribed as a preventive measure for gastric and duodenal ulcers while taking drugs from the NPS group, as well as acetylsalicylic acid.

Instructions for use

Tablet form

The tablets are thoroughly chewed or dissolved, and it is not necessary to drink water. Use one or two tablets up to four times a day. It is recommended to take the medicine at bedtime, as well as 1-2 hours after eating.

In acute lesions of the esophagus, the medicine is taken after meals at short intervals. But no more than six times a day. More than 12 tablets per day are strictly contraindicated.

The course of Maalox therapy should not exceed three months.

In violation of the diet, you can take one or two tablets once.

If there are painful sensations in the stomach associated with high acidity, you can chew 1 or 2 tablets.

When taking the drug, follow the instructions

Suspension Maalox

Before use, the bottle is thoroughly shaken, and the medicine bag is well kneaded to achieve uniformity. The substance contained in the sachets is used without dissolving in water.

In acute lesions of the esophagus, the medicine is taken 30-60 minutes after eating, and in case of an ulcer, half an hour after a meal.

The course of therapy is not more than three months.

special instructions

If the patient has impaired renal function, when taking Maalox, he needs special control. If there were side effects, you must stop using immediately. In patients with renal insufficiency, high doses of the drug are contraindicated, as they can cause the development of microcytic anemia, dementia or encephalopathy.

If the medicine is used for a long time, phosphorus salts should be supplied with food to patients.

Reception during pregnancy and lactation

Animal studies have not given a clear answer to the question of whether the drug affects the fetus. To date, the negative impact of Maalox on the intrauterine development of the unborn baby has not yet been described in medical practice.

But since there are no reliable studies, Maalox is allowed only if the therapeutic effect is more important for the mother than the likely risk to the fetus.

In large doses, the appointment of medicines is not recommended. The use of Maalox is allowed only in small courses.

into blood and breast milk active substances the drug is practically not absorbed, so it is allowed to take it during breastfeeding.

Drug Interactions

When using Maalox and Norfloxacin, Ketonazole, Indomethacin or Digoxin at the same time, the absorption of the latter slows down, so therapy may not give the desired effect.

If the drug is used for ulcers as a prophylactic, it is necessary to withstand at least two to three hours between doses of the drug, otherwise the effectiveness of NSAIDs will decrease.

The process of moving food through the gastrointestinal tract is reduced by drugs from the group of M-anticholinergics, thereby increasing the time of the action of Maalox. This must be taken into account when drug interaction these drugs.

Overdose of Maalox

In very rare cases, an overdose of this drug occurs. If the drug is used for a long time in large doses, the following pathological conditions may develop:

• hypocalcemia and/or hypophosphatemia;
• hyperaluminemia and/or hypermagnesemia;
• in the analysis of urine, the level of calcium may increase;
• on the part of the central nervous system, the development of deviations;
• development of encephalopathy;
• calcium deposits in the urinary tract and kidneys, which inhibits the functioning of the urinary system.

There is a possibility of developing acute renal failure.

In elderly patients, intestinal peristalsis can decrease sharply, which threatens with intestinal obstruction.

If the above symptoms appear, the patient needs hospitalization.

Side effects

Maalox is well tolerated in most cases. In case of an overdose or individual intolerance, the following undesirable symptoms may occur:

• loss of appetite;
• feeling of vomiting or nausea;
• heaviness in the epigastrium;
• chair problems.

Symptoms are not dangerous to health and quickly disappear with a decrease in dosage or complete withdrawal of the drug.

Terms and conditions of storage

The drug is stored out of the reach of children at a temperature not exceeding 25 0 C.

Shelf life - no more than three years.

After the expiration date, which is indicated on the package of the drug, it is contraindicated to use it.

Price policy

Medicine in tablet form - approximately 230 rubles per pack.

Sachets of 4.3 ml, six pieces per pack - about 160 rubles.

Suspension with a volume of 250 ml in a bottle - about 500 rubles.

Suspension of 15 ml, thirty pieces per pack - the cost is about 780 rubles.

Analogues of Maalox

Almagel is a good analogue of Maalox

There are others medications, which are worthy competition to Maalox. But in order to replace this drug with an analogue, you must first consult with your treating gastroenterologist.

A good drug with antacid qualities is Almagel. The agent is available in the form of a suspension or gel, has an enveloping effect and protects the gastric mucosa from the damaging effects of chemical agents.

It also perfectly replaces Maalox with Alumag. It is used with success in many pathologies of the gastrointestinal tract, especially in reflux esophagus and esophageal hernia. This analogue is inexpensive, so it is suitable for patients with limited finances. The components of the drug in the stomach react with hydrochloric acid, resulting in the formation of chlorides, which normalize the pH level.

In addition, the drug Gastal Andre effectively normalizes the level of acidity. The medicine well stops heartburn attacks and will help relieve intoxication caused by drug poisoning.

You can stop the symptoms of the stomach and duodenum with the help of the drug Stomalox.

Ajiflux is a choleretic drug, so it can be used for dyskinesia.

The drug Almol acts almost instantly, after a few minutes the unpleasant symptoms go away. But the drug only works for about an hour.

Video: Heartburn Medication Guide

Antacid drug

Active ingredients

Magnesium hydroxide (magnesium hydroxide)
- algeldrate (aluminum hydroxide gel) (algeldrate)

Release form, composition and packaging

◊ Chewable tablets white, round, flat-cylindrical, chamfered and engraved "Mx".

Excipients: starch with sucrose (confectionery sugar) - 192 mg, sorbitol - 125 mg, - 10 mg, magnesium stearate - 7.2 mg, peppermint flavor - 3.6 mg, sodium saccharinate - 3 mg, sucrose - 59.2 mg.

◊ Chewable tablets (sugar free) from white to yellowish color with slight marbling, round, flat-cylindrical, chamfered, engraved "MAALOX" on one side and "sans sucre" on the other, with a lemon scent.

Excipients: liquid sorbitol (non-crystallizing) - 157 mg (equivalent to 109.9 mg of sorbitol), maltitol - 632.62 mg, magnesium stearate - 16.36 mg, lemon flavor (flavors, natural flavors, acacia gum (E414), citric acid (E330) , butylhydroxyanisole (E320)) - 17 mg, sodium saccharinate - 1.9 mg, glycerol 85% - 30 mg (equivalent to 25.5 mg glycerol), talc - 32.72 mg.

10 pieces. - blisters (1) - packs of cardboard.
10 pieces. - blisters (2) - packs of cardboard.
10 pieces. - blisters (4) - packs of cardboard.

◊ Suspension for oral administration in the form of a white or almost white liquid, reminiscent of milk, with a mint odor.

Excipients: concentrated hydrochloric acid - 21.3 mg, citric acid monohydrate - 9.83 mg, oil - 1.89 mg, mannitol - 37.5 mg, methyl parahydroxybenzoate - 15 mg, propyl parahydroxybenzoate - 7.5 mg, sodium saccharinate - 4.21 mg, sorbitol 70% - 214.29 mg, hydrogen peroxide 30% - 9.75 mg, purified water - 4746.59 mg.

15 ml - sachets (sachets) (30) - packs of cardboard.

◊ Suspension for oral administration white, homogeneous after shaking.

Excipients: hydrochloric acid 10% - 0.52815 g, citric acid monohydrate - 0.0655 g, peppermint leaf oil - 0.0126 g, mannitol - 0.25 g, domifene bromide - 0.00422 g, sodium saccharinate - 0.028 g, sorbitol 70% - 1.429 g, hydrogen peroxide 30% - 0.065 g, purified water - up to 100 ml.

250 ml - polyethylene terephthalate bottles (1) - cardboard packs.

pharmachologic effect

An antacid drug. Neutralizes free hydrochloric acid of gastric juice without causing its secondary hypersecretion. In addition, an increase in the pH of gastric juice when taking Maalox leads to a decrease in the activity of pepsin in gastric juice. The drug also has an adsorbing and enveloping effect, due to which the impact of damaging factors on the mucous membrane of the esophagus and stomach is reduced.

Pharmacokinetics

Indications

- peptic ulcer of the stomach and duodenum in the acute phase;

- acute gastroduodenitis;

- chronic gastroduodenitis with normal or increased secretory function in the acute phase;

- hernia of the esophageal opening of the diaphragm;

- reflux esophagitis;

- dyspeptic phenomena, such as discomfort, gastralgia, heartburn, sour eructation (after excessive consumption of ethanol, nicotine, coffee, medications / including NSAIDs, GCS /, diet errors).

Contraindications

- severe degree;

- hypophosphatemia;

- intolerance to fructose;

- glucose-galactose malabsorption syndrome, sucrase / isomaltase deficiency, (due to the presence of sucrose and sorbitol in the preparation) (for chewable tablets, for suspension in sachets, for suspension in vials);

- intolerance to maltitol (for chewable tablets without sugar);

- children and adolescents up to 15 years;

- hypersensitivity to active substances and other components of the drug.

Carefully the drug should be used in patients with porphyria who are on hemodialysis; with Alzheimer's disease; during pregnancy; for chewable tablets - for diabetes mellitus (due to the presence of sucrose in the preparation).

Dosage

Tablets

Tablets should be sucked or chewed thoroughly.

Adults and teenagers over 15 years old the drug is prescribed 1-2 tab. 3-4 times / day 1-2 hours after meals and at night.

At reflux esophagitis the drug is taken after a short period of time after a meal.

The maximum frequency of reception - 6 times / day. Do not take more than 12 tablets / day.

Duration of admission should not exceed 2-3 months.

discomfort after errors in the diet, take 1-2 tab. once.

Suspension in sachets

Before use, the suspension in the sachet should be homogenized by carefully kneading it between the fingers. The contents of the sachet are taken in undissolved form.

Maalox is taken 1 sachet with a suspension (15 ml) usually 1-2 hours after a meal and at night, as well as in case of epigastric pain or heartburn. Daily dose should not exceed 6 sachets (90 ml of suspension per day).

At reflux esophagitis the drug is taken 30-60 minutes after a meal.

At stomach ulcer the drug is taken 30 minutes before a meal.

For occasional use, such as

At patients with impaired renal function avoid the use of the drug Maalox in the form of a suspension in a sachet in high doses and / or for a long time.

Suspension in vials

Shake the bottle before use.

Assign 15 ml (1 tablespoon) 3-4 times a day 1-2 hours after meals and at night. The dose should not exceed 6 tablespoons per day.

At reflux esophagitis the drug is taken shortly after a meal.

The course of treatment should not exceed 2-3 months.

For occasional use, such as discomfort after errors in the diet, take 15 ml once.

Side effects

Frequency detection unwanted effects(according to WHO classification): infrequently (≥0.1% and<1%); частота неизвестна (по имеющимся данным оценить частоту возникновения не представляется возможным).

From the immune system: frequency unknown - hypersensitivity reactions, anaphylactic reactions.

Allergic reactions: frequency is unknown - itching, urticaria, angioedema.

From the digestive system: infrequently - diarrhea, constipation.

From the side of metabolism: the frequency is unknown - hypermagnesemia, hyperaluminemia, hypophosphatemia (with long-term treatment or high doses, or when taken in standard doses with a low phosphate content in food), which can lead to increased bone resorption, hypercalciuria, osteomalacia.

Overdose

Symptoms: diarrhea and vomiting are possible. In patients at risk, taking the drug in high doses may cause or exacerbate intestinal obstruction or intestinal obstruction.

Treatment: aluminum and magnesium are excreted in the urine. Fluid replacement and forced diuresis are performed. Patients with renal insufficiency require hemodialysis or peritoneal dialysis.

drug interaction

When used simultaneously with quinidine possible increase in serum concentrations of quinidine and the development of an overdose of quinidine.

When taken simultaneously with Maalox, the absorption from the gastrointestinal tract of the following drugs is reduced: blockers of histamine H 2 receptors, propranolol, atenolol, cefdinir, cefpodoxime, metoprolol, chloroquine, prostacyclins, diflunisal, digoxin, bisphosphonates, ethambutol, isoniazid, fluoroquinolones, GCS (described for prednisolone and dexamethasone), indomethacin, ketoconazole, lincosamamine phenothiazine, penicillamine, rosuvastatin, iron salts, levothyroxine. In the case of a 2-hour interval between taking these drugs and Maalox and a 4-hour interval between taking fluoroquinolones and Maalox, in most cases this undesirable interaction can be avoided.

When Maalox is co-administered with polystyrene sulfonate (kyexalate) caution should be exercised because of the possible risk of reducing the efficiency of potassium binding by the resin and the development of metabolic alkalosis in patients with renal insufficiency (for aluminum hydroxide and magnesium hydroxide) and intestinal obstruction (for aluminum hydroxide).

When aluminum hydroxide is combined with citrates possible increase in plasma concentrations of aluminum, especially in patients with renal insufficiency.

special instructions

Aluminum hydroxide can cause constipation, an overdose of magnesium salts can lead to a weakening of intestinal motility; in high-risk patients (patients with renal insufficiency, the elderly), taking high doses of the drug may cause or exacerbate intestinal obstruction and intestinal obstruction.

Aluminum hydroxide is poorly absorbed from the gastrointestinal tract, so systemic exposure is rare in patients with normal renal function. However, long-term treatment, use of the drug in excessively high doses, or use of the drug at usual doses against the background of a decrease in phosphate intake from food can lead to phosphate deficiency (due to the binding of aluminum to phosphate), which is accompanied by increased bone resorption and hypercalciuria with the risk of developing osteomalacia. Treatment of patients at risk of developing phosphate deficiency or long-term use of the drug should be carried out under medical supervision.

In renal failure, an increase in plasma concentrations of magnesium and aluminum is possible. In these patients, with long-term use of the drug Maalox in high doses, encephalopathy, dementia, microcytic anemia, or aggravation of osteomalacia caused by dialysis may develop.

If during treatment the symptoms of the gastrointestinal tract persist for more than 10 days or there is a deterioration in the condition, then the diagnosis should be clarified and the treatment should be corrected.

A 2-hour interval between the use of Maalox and other drugs and a 4-hour interval between taking Maalox and fluoroquinolones should be observed (see section "Drug Interactions").

Long-term use of Maalox in renal failure should be avoided. When prescribing Maalox, patients with mild to moderate renal insufficiency should carefully monitor plasma concentrations of aluminum and magnesium, and if they increase, the use of the drug should be immediately discontinued.

Despite the fact that the drug is available without a prescription, it is recommended to consult a doctor before using the drug during pregnancy and lactation (breastfeeding), as well as in adolescents.

Aluminum hydroxide with a low content of phosphates in food can lead to the development of phosphorus deficiency in the body. Therefore, when using it, especially for a long time, it is necessary to ensure sufficient intake of phosphates from food.

The preparation is permeable to x-rays.

When using the drug in patients with diabetes, the presence of sucrose in the composition of Maalox chewable tablets should be taken into account.

Influence on the ability to drive vehicles and control mechanisms

The drug in the form of a suspension in sachets does not affect the ability to drive vehicles and work with mechanisms.

Pregnancy and lactation

To date, no specific teratogenic effects have been identified when using Maalox during pregnancy, however, due to the lack of clinical experience with its use in pregnancy, the appointment is possible only if the potential benefit of therapy for the mother justifies the potential risk to the fetus.

When using the drug in accordance with the dosing regimen, the absorption of combinations of aluminum hydroxide and magnesium salts in the mother's body is limited, therefore Maalox is recognized as compatible with breastfeeding.

IN preclinical studies animals have not received clear indications of the presence of a teratogenic effect in aluminum hydroxide and magnesium hydroxide.

Application in childhood

Use in children and adolescents under the age of 15 is contraindicated.

For impaired renal function

Contraindicated in severe renal failure.

Use in the elderly

Do not use the drug after the expiration date indicated on the package.