Amoxiclav instructions for use of tablets for adults 500. Antibiotic Amoxiclav: instructions for use, pharmacological properties, indications, dosage

Amoxiclav
Buy Amoxiclav in pharmacies

DOSAGE FORMS
coated tablets 875mg/125mg
film-coated tablets 875mg+125mg

MANUFACTURERS
Lek d.d. (Slovenia)

GROUP
Combined antimicrobials

COMPOSITION
Active substances: 875 mg of amoxicillin in the form of trihydrate and 125 mg of clavulanic acid in the form of potassium salt.

INTERNATIONAL NON-PROPRIETARY NAME
Amoxicillin + Clavulanic acid

SYNONYMS
Amoxiclav Quiktab, Arlet, Augmentin, Augmentin EC, Augmentin SR, Klamosar, Medoklav, Panklav, Ranklav, Rapiclav, Sinulox, Sinulox RTU, Flemoclav Solutab, Ecoclave

PHARMACHOLOGIC EFFECT
The drug is a combination of amoxicillin and clavulanic acid. Amoxicillin is a semi-synthetic penicillin (beta-lactam antibiotic) that inhibits one or more enzymes (often referred to as penicillin-binding proteins, PBPs) in the biosynthesis pathway of peptidoglycan, which is an integral structural component of the bacterial cell wall. Inhibition of peptidoglycan synthesis leads to a loss of cell wall strength, which usually leads to lysis and death of microorganism cells. Amoxicillin is destroyed by the action of beta-lactamases produced by resistant bacteria, thus, the spectrum of activity of amoxicillin alone does not include microorganisms that produce these enzymes. Clavulanic acid is a beta-lactam structurally related to penicillins. It inhibits some beta-lactamases, thereby preventing the inactivation of amoxicillin and extending its spectrum of activity to include bacteria normally resistant to amoxicillin as well as to other penicillins and cephalosporins. By itself, clavulanic acid does not have a clinically significant antibacterial effect. The drug has a bactericidal effect in vivo on the following microorganisms: Gram-positive aerobes. Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes. Gram-negative aerobes. Enterobacter spp, Escherichia coli, Haemophilus influenza, Species of the genus Klebsiella, Moraxella catarrhalis (Branhamella catarrhalis). The drug has a bactericidal effect in vitro on the following microorganisms (however, the clinical dependence is still unknown). Gram-positive aerobes. Bacil Hs anthracis. Species of the genus Corynebacterium, Enterococcus faecalis, Enterococcus faecium, Listeria monocytogenes, Nocardia asteroids, Coagulase-negative staphylococci (including Staphylococcus epidermidis) Streptococcus agalaciiae. Other species of the genus Streptococcus Streptococcus viridians. Gram-positive anaerobes. Species of the genus Clostridium, Species of the genus Peptococcus, Species of the genus Peptostreptococcus. Gram-negative aerobes. Bordetella pertussis, Species of the genus Brucella, Gardnerella vaginalis, Helicobacter pylori, Species of the genus Legionella, Neisseria gonorrhoeae, Neisseria meningitides, Pasteurella multocida, Proteus mirabilis, Proteus vulgaris, Species of the genus Salmonella, Species of the genus Shigella, Vibrio cholerae, Yersinia enterocolitica. Gram-negative anaerobes. Species of the genus Bacteroides (including Bacteroides fragilis), Species of the genus Fusobacterium. Others: Borrella burgdorferi, Chlamydia spp., Leptospira icterohaemorrhagiae, Treponema pallidum. Some strains of these bacterial species produce beta-lactamase, which contributes to their insensitivity to amoxicillin monotherapy. Pharmacokinetics. The main pharmacokinetic parameters of amoxicillin and clavulanic acid are similar. Amoxicillin and clavulanic acid are highly soluble in aqueous solutions with a physiological pH value and after taking the drug inside, they are quickly and completely absorbed from the gastrointestinal tract (GIT). The absorption of the active substances of amoxicillin and clavulanic acid is optimal if taken at the beginning of a meal. The bioavailability of amoxicillin and clavulanic acid after oral administration is about 70%. Peak plasma concentrations are reached approximately 1 hour after ingestion. The maximum concentration values ​​​​are for amoxicillin (depending on the dose) 3-12 μg / ml, for clavulanic acid - about 2 μg / ml. When using the drug, plasma concentrations of amoxicillin / clavulanic acid are similar to those with oral administration of the corresponding doses of amoxicillin or clavulanic acid separately in equivalent doses. Both components are characterized by a good volume of distribution in various organs, tissues and body fluids (including lungs, abdominal organs; adipose, bone and muscle tissues; pleural, synovial and peritoneal fluids; skin, bile, urine, purulent discharge, sputum, interstitial fluid). Plasma protein binding is moderate: 25% for clavulanic acid and 18% for amoxicillin. The volume of distribution is about 0.3-0.4 l/kg for amoxicillin and about 0.2 l/kg for clavulanic acid. Amoxicillin and clavulanic acid do not cross the blood-brain barrier in non-inflamed meninges. Amoxicillin (like most penicillins) is excreted in breast milk. IN breast milk trace amounts of clavulanic acid were also found. Amoxicillin and clavulanic acid cross the placental barrier. Amoxicillin is excreted primarily by the kidneys, while clavulanic acid is eliminated via both renal and extrarenal mechanisms. After a single oral administration of one tablet of 250 mg / 125 mg or 500 mg / 125 mg, approximately 60-70% of amoxicillin and 40-65% of clavulanic acid are excreted unchanged in the urine during the first 6 hours. About 10-25% of the initial dose of amoxicillin is excreted in the urine as inactive penicillic acid. Clavulanic acid in the human body undergoes intensive metabolism with the formation of 2,5-dihydro-4-(2-hydroxyethyl)-5-oxo-1H-pyrrole-3-carboxylic acid and 1-amino-4-hydroxy-butan-2-one and is excreted in urine and feces. The mean half-life of amoxicillin/clavulanic acid is approximately one hour, and the mean total clearance is approximately 25 L/h in healthy patients. In the course of various studies, it was found that the excretion of amoxicillin in the urine within 24 hours is approximately 50-85%, clavulanic acid - 27-60%. The greatest amount of clavulanic acid is excreted during the first 2 hours after ingestion. Patients with impaired liver function. In patients with severe kidney failure the half-life increases to 7.5 hours for amoxicillin and up to 4.5 hours for clavulanic acid. For patients with impaired liver function, the dose of the drug should be selected with caution, constant monitoring of the state of the liver is necessary. Both components are removed by hemodialysis and minor amounts by peritoneal dialysis.

INDICATIONS FOR USE
Infections caused by susceptible strains of microorganisms: infections of the upper respiratory tract and ENT organs (including acute and chronic sinusitis, acute and chronic otitis media, retropharyngeal abscess, tonsillitis, pharyngitis); lower respiratory tract infections (incl. acute bronchitis with bacterial superinfection, Chronical bronchitis, pneumonia); infections urinary tract; infections in gynecology; infections of the skin and soft tissues, as well as wounds from human and animal bites; bone and connective tissue infections; infections biliary tract(cholecystitis, cholangitis); odontogenic infections.

CONTRAINDICATIONS
Hypersensitivity to the components of the drug; a history of hypersensitivity to penicillins, cephalosporins and other beta-lactam antibiotics, cholestatic jaundice and / or other liver dysfunction caused by taking amoxicillin / clavulanic acid in history; Infectious mononucleosis and lymphocytic leukemia.

SIDE EFFECT
From the digestive system: loss of appetite, nausea, vomiting, diarrhea, abdominal pain, gastritis, stomatitis, glossitis, black "hairy" tongue, darkening of tooth enamel, hemorrhagic colitis (may also develop after therapy), enterocolitis, pseudomembranous colitis, violation liver function, increased activity of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and / or plasma bilirubin levels, liver failure (more often in the elderly, men, with long-term therapy), cholestatic jaundice, hepatitis. Allergic reactions: itching, urticaria, erythematous rashes, multiforme exudative erythema, angioedema, anaphylactic shock, allergic vasculitis, exfoliative dermatitis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, a syndrome similar to serum sickness, toxic epidermal necrolysis. From the hematopoietic system and lymphatic system: reversible leukopenia "(including neutropenia), thrombocytopenia, hemolytic anemia, reversible increase in prothrombin in time (when used together with anticoagulants), reversible increase in bleeding time, eosinophilia, pancytopenia, thrombocytosis, agranulocytosis. From the side of the central nervous system: dizziness, headache, convulsions (may occur in patients with impaired renal function when taking high doses of the drug), hyperactivity. Feelings of anxiety, insomnia, behavioral changes, agitation. From the urinary system: interstitial nephritis, crystalluria, hematuria. Other: candidiasis and other types of superinfection.

INTERACTION
Antacids, glucosamine, laxatives, aminoglycosides slow absorption, ascorbic acid increases absorption. Diuretics, allopurinol, phenylbutazone; non-steroidal anti-inflammatory drugs and other drugs that block tubular secretion (probenecid) increase the concentration of amoxicillin (clavulanic acid is excreted mainly by glomerular filtration). The simultaneous use of the drug and methotrexate increases the toxicity of methotrexate. Appointment in conjunction with allopurinol increases the incidence of exanthema. Avoid concomitant use with disulfiram. Reduces the effectiveness of drugs, during the metabolism of which para-aminobenzoic acid is formed, ethinyl estradiol - the risk of bleeding "breakthrough". The literature describes rare cases of an increase in the international normalized ratio (MNR) in patients with the combined use of acenocoumarol or warfarin and amoxicillin. If necessary, simultaneous use with anticoagulants and prothrobin time or MHO should be carefully iterated when prescribing or discontinuing the drug. The combination with rifampicin is antagonistic (mutual weakening of the antibacterial effect). The drug should not be used simultaneously in combination with bacteriostatic antibiotics (macrolides, tetracyclines), sulfonamides due to a possible decrease in the effectiveness of the drug. The drug reduces the effectiveness of oral contraceptives.

METHOD OF APPLICATION AND DOSAGE
inside. The dosage regimen is set individually depending on the age, body weight, kidney function of the patient, as well as the severity of the infection. The drug is recommended to be taken at the beginning of a meal for optimal absorption and to reduce possible side effects from the digestive system. The course of treatment is 5 - 14 days. The duration of the course of treatment is determined by the attending physician. The course should not last more than 14 days without a second medical examination. Children under 12 years old. The dose is prescribed depending on age and body weight. Recommended dosage regimen: 40 mg/kg/day in 3 divided doses. Children weighing 40 kg or more should be given the same doses as adults. For children under the age of 6 years, it is more preferable to take a suspension of the drug. Adults and children over 12 years of age (or over 40 kg body weight). The usual dose for mild to moderate infections is 1 tablet every 12 hours, for severe infections and respiratory tract infections, 1 tablet every 8 hours. Since the 250mg + 125mg and 500mg-125mg tablets of the combination of amoxicillin and clavulanic acid contain the same amount of clavulanic acid -125mg, then 2 tablets of 250mg + 125mg are not equivalent to 1 tablet of 500mg + 125mg. Dosage for odontogenic infections: 1 tablet every 12 hours for 5 days. Patients with impaired renal function. Dose adjustments are based on the maximum recommended dose of amoxicillin and are based on creatinine clearance (CC) values. Adults and children over 12 years of age (or over 40 kg body weight). QC> 30 ml / min: dose adjustment is not required. With anuria, the interval between dosing should be increased to 48 hours or more. Tablets 875 mg + 125 mg should only be used in patients with CC> 30 ml / min. Patients with impaired liver function. The drug should be taken with caution. It is necessary to conduct regular monitoring of liver function.

OVERDOSE
There are no reports of death or life-threatening side effects due to an overdose of the drug. In most cases, overdose symptoms include gastrointestinal disorders (abdominal pain, diarrhea, vomiting). Anxiety, insomnia, dizziness, and in isolated cases, convulsive seizures are also possible. In case of an overdose, the patient should be under the supervision of a physician, treatment is symptomatic. In case of recent intake (less than 4 hours), it is necessary to perform gastric lavage and prescribe activated charcoal to reduce absorption. Amoxicillin/clavulanic acid is removed by hemodialysis.

SPECIAL INSTRUCTIONS
Carefully. Pseudomembranous colitis in history, diseases of the gastrointestinal tract, liver failure, severe renal dysfunction, pregnancy, lactation, while used with anticoagulants. Use during pregnancy and during breastfeeding. During pregnancy and lactation, the drug is used only if the intended benefit to the mother outweighs the potential risk to the fetus and child. During the course of treatment, it is necessary to monitor the state of the function of the hematopoietic organs, liver, kidneys. In patients with severely impaired renal function, an adequate dose adjustment or an increase in the intervals between doses is required. In order to reduce the risk of side effects from the gastrointestinal tract, the drug should be taken with food. It is possible to develop superinfection due to the growth of microflora insensitive to it, which requires an appropriate change. antibiotic therapy. In patients with hypersensitivity to penicillins, cross-allergic reactions with cephalosporin antibiotics are possible. In women with premature rupture of membranes, it has been found that prophylactic therapy with amoxicillin + clavulanic acid may be associated with an increased risk of neonatal necrotizing colitis. In patients with reduced diuresis, crystalluria very rarely occurs. During the use of large doses of amoxicillin, it is recommended to take a sufficient amount of fluid and maintain adequate diuresis to reduce the likelihood of amoxicillin crystal formation. Laboratory tests: High concentrations of amoxicillin give a false positive reaction to urine glucose when using Benedict's reagent or Fehling's solution. Enzymatic reactions with glucosidase are recommended. Special precautions for the disposal of unused medicinal product. There is no need for special precautions when destroying an unused drug. Influence on the ability to drive vehicles and engage in other activities that require concentration and speed of psychomotor reactions. Due to the possibility of developing side effects from the central nervous system, such as: dizziness, headache, convulsions, during treatment, care should be taken when driving and engaging in other activities that require concentration and speed of psychomotor reactions.

STORAGE CONDITIONS
Store in a dry place, out of the reach of children, at a temperature not exceeding 25 C.

Amoxiclav 500/125 belongs to the group antibacterial agents penicillin series, used to combat many diseases caused by infection of a bacterial nature. This is a complex drug preparation, consisting of two components with antibacterial activity.

Amoxiclav is a product of an Austrian pharmaceutical company.

The medication is available in the following forms:

• in tablets with a dosage of 250 mg / 125 mg with a thin shell soluble in the intestine;
• in tablets with a dosage of 500 mg / 125 mg with an enteric coating;
• in the form of tablets for resorption, dissolution in water - Amoxiclav Quiktab with a dosage of 500 mg / 125 mg;
• in the form of a powder that allows you to prepare a suspension for children;
• in the form of a powder, for the preparation of intravenous injections.

The tablet form of Amoxiclav includes the following components that actively affect the body:

• amoxicillin 500 mg;
• clavulanic acid 125 mg.

Tablets, in addition to active substances, consist of the following auxiliary components that do not have a therapeutic effect:

• cellulose;
• silicon dioxide;
• polysorbate;
• titanium dioxide;
• magnesium stearate.

Amoxiclav Quiktab tablets, in addition to active ingredients, consist of the following auxiliary ingredients:

• aspartame;
• silicon dioxide;
• iron oxide;
• castor oil;
• flavors.

The suspension, along with the active ingredients, includes in its composition substances that do not have a therapeutic effect on bacteria:

• mannitol;
• sodium citrate;
• sodium saccharin;
• sodium benzoate.

For your information. The injection powder contains only active ingredients.

Pharmacological action, pharmacodynamics and pharmacokinetics

Instructions for use indicate the presence of the following pharmacological activity of Amoxiclav:

• penicillin-derived drug has a bactericidal effect, disrupts cell synthesis. Thus destroying pathogenic microorganisms;
• clavulanic acid enhances the effectiveness of amoxicillin. The second active component of Amoxiclav also has an antimicrobial effect;
• the drug is active against gram-positive anaerobes;
• the medicine is effectively taken with gram-negative anaerobes.

Amoxiclav quickly acts on pathogenic microorganisms. Already 60 minutes after its administration, the highest concentration of active components in plasma is determined. The active component of the antibiotic is absorbed into circulatory system from the intestines, from where it spreads throughout the body. The drug is excreted through the urinary system within an hour.

In what cases is Amoxiclav prescribed?

Indications for prescribing medication are:

• infectious ENT diseases;
• urinary infections;
• pathology of the bronchi, lungs caused by infections;
• bacterial processes of the upper respiratory tract;
• gynecological infections, postpartum inflammation;
• infectious processes of connective tissues;
• diseases of bone tissue;
• skin infectious diseases, post-burn conditions;
• inflammatory processes of bones, joints;
• infected processes of the abdominal cavity;
• odotogenic infections;
• infection of the teeth, jaw;
• preoperative, postoperative period.

Important! Amoxiclav is taken only to eliminate an infection that marks sensitivity to the penicillin series.

Instructions for use and dosage

It is recommended to drink a penicillin-containing drug after consulting a doctor. It is important to find out the presence of sensitivity of bacteria to antibiotics by conducting bacteriological studies. Recommendations for dosage, frequency of administration, duration of the treatment course are given individually. An assessment is made of the patient's condition, age, type of disease, its severity. Before starting treatment, it is necessary to make sure that there is no hypersensitivity to Amoxiclav. It is advisable to do an allergy test.

Tablets 500 mg + 125 mg

The tableted form of Amoxiclav is prescribed for adults, children over 12 years of age. In this case daily dose should not exceed 600 mg.

• uncomplicated pathology - 1 tab. four times a day;
• mild infection - 1 tab. twice a day;
• complicated course of the disease - 1 tab. up to 6 times a day;
• odotogenic infection - 1 tab. four times or twice a day.

If treatment is required for a patient who suffers from liver failure, then between doses it is necessary to increase the break to 12 hours. In severe kidney disease, the interval between doses is recommended to be increased to 24 hours, provided intravenous administration Amoxiclav.

Therapy of the child population is carried out by Amoxiclav in suspension, diluted to measure with distilled water. Permissible dosage per day is up to 45 mg of a penicillin preparation per 1 kg of the child's weight.

Amoxiclav in injections

Amoxiclav injections are usually given intravenously. In exceptional situations, intramuscular injection is allowed, taking into account the following dose:

• older than 12 years, the antibiotic is administered 1.2 g 3 times a day. Severe course is treated with a four-time injection;
• up to 12 years, the dosage is calculated individually, based on the weight of the child. For 1 kg of weight there are 30 mg of Amoxiclav four times a day;
• for babies up to 3 months, the dosage is calculated from 30 mg per 1 kg of the child's weight twice a day.

Important! The prepared injection powder must be administered within 15 minutes. The prepared solution must not be frozen.

If after 2-3 days after the start of treatment the expected result is not observed, then it is necessary to change the therapeutic tactics with a change in the drug group. Amoxiclav has proven effective only against bacterial infections.

During pregnancy and lactation

The appointment of Amoxiclav to pregnant women is made only if the expected benefit to the expectant mother is higher than the expected harm to the child. It is especially harmful to carry out antibiotic therapy in the first trimester.

In the second, third trimester, the medication is prescribed subject to the exact observance of the dose. During breastfeeding, the drug is not used. This is due to the fact that its active components enter the child's body through breast milk.

drug interaction

With the parallel use of Amoxiclav with some groups of medicines, the following undesirable reactions may occur:

• with ascorbic acid, the absorption of the antibiotic is accelerated;
• with laxatives, there is a slowdown in absorption;
• with non-steroidal anti-inflammatory drugs, an increased concentration of Amoxiclav is observed;
• with anticoagulants, the effectiveness of antithrombotic agents decreases;
• with Rifampicin, the antibacterial effect is weakened;
• with tetracyclines, the effectiveness of antibiotic therapy is reduced;
• with oral contraceptives, their effectiveness may be reduced.

Can I drink alcohol while taking the drug

It is forbidden to take Amoxiclav simultaneously, even with low-alcohol drinks. This can lead to an increase in the negative impact on the liver, an increase in the number of side effects.

Contraindications, side effects and overdose

Before starting the use of Amoxiclav, it is necessary to take into account the presence of the following contraindications:

• jaundice;
• lymphocytic leukemia;
• mononucleosis;
• allergic reaction to penicillin-containing drugs;
• liver diseases;
• kidney diseases.

If there is hypersensitivity to active ingredients, the recommended dosage is exceeded, the frequency of Amoxiclav use is increased, then side effects may develop in the form of:

• nausea;
• decreased appetite;
• diarrhea;
• vomiting;
• abdominal pain;
• itching;
• skin rash;
• puffiness;
• anaphylactic shock;
• dermatitis;
• jade;
• headache;
• dizziness;
• convulsive state;
• dysbacteriosis causing a fungal infection;
• bacterial resistance.

Cases of overdose lead to an increase in side effects, the severity of their manifestations increases. Usually, an incorrectly calculated dose of Amoxiclav causes vomiting, diarrhea, and nervous overexcitation. More severe situations are accompanied by convulsions. If symptoms of an overdose appear after taking, then you should call a doctor, do a gastric lavage, take activated charcoal.

To replace the recommended intake of the following drugs with a wide spectrum of action:

• Renklava;
• Amoxivana;
• Flemoklava;
• Augmentina;
• Panclava.

The replacement of Amoxiclav should be carried out by a doctor, as well as the calculation of the recommended dosage and frequency of administration.

Antibiotic therapy with Amoxiclav helps fight various infections. The drug is usually well tolerated by patients of different age categories.

Search service for generics in Moscow

Loving a woman in bed for a long time or completely surrendering to her man is one of the main pleasures of an adult. Not always sexual arousal soars from zero to heaven. It happens that the body needs help in order to tune in to intimacy itself and get a partner. To do this, we offer to buy generics in Moscow. Inexpensive, proven in terms of composition, and most importantly - effective drugs increase potency for men, make sexual intercourse long and deeply satisfying.

Generics.RU: what is it and how does it work?

Generics.RU- an aggregator through which you can order cheap generics in online pharmacies, whose prices and delivery terms will suit you. The site issues drugs on request, sorting them by cost, you choose the right one and order courier delivery around the city. Available OTC medications, dietary supplements and prescription drugs to increase potency.

We act as an intermediary between the client and the online pharmacy. The automated system searches for available generics and dietary supplements. You see the final search result, the most advantageous offer for the current day is taken from each site and displayed on our website (search results are updated once a day). Our database contains only sites that have existed for more than 5 years. This allows you to work only with reliable online pharmacies, suppliers, minimize risks and get lower prices for you.

You fill out an application for the drug or dietary supplement you are interested in, our manager checks and confirms your application, clarifies your wishes (prescription for prescription drugs), after that the purchase department redeems your order, the courier picks it up from the pharmacy and brings it to your home.

What can be found on our website?

The pharmacies we search for offer:

➤ Viagra(sildenafil citrate). A classic remedy for improving erection with proven effectiveness. Thanks to him, a man is quickly excited, becomes hardy in bed and is able to deliver sexual pleasure. The drug treats impotence, makes an erection powerful and long-lasting.

➤ Cialis(tadalafil). Another popular remedy for the qualitative improvement of sex. With proper use of these pills, not only men's health, but also mood is steadily improving. The action persists for 1-1.5 days.

➤ Levitra(vardenafil). Cheap generic for erection restoration and treatment of a number of problems associated with the genitourinary tract. Erection becomes powerful 2-3 hours after taking sucking tablets or powder dissolved in water, the action lasts 6-8 hours.

➤ Avanafil. Fast-acting erection improvement pills: you will see the result 15-20 minutes after taking it, when you start intimate communication with a partner. The effect will last 5-6 hours.

➤ Dapoxetine. A drug that prolongs sexual intercourse and provokes spasms of the muscles of the small pelvis, which are necessary for ejaculation. Valid for 3-4 hours. It is used for sexual dysfunction and premature ejaculation.

⭐All products are certified! ⭐

For women

Also, in pharmacies offering to buy generics in Moscow through our aggregator website, funds for women are presented - stimulating drops, tablets, dietary supplements, capsules. Women's preparations are mainly natural in composition, taken 15-20 minutes before sex, increase the secretion of lubrication and increase the sensitivity of the genitals.

You can also order from the catalog:

• condoms;
• combined tablets (2-3 active substances and in 1 tool);
• general strengthening dietary supplements that gently help to cope with erectile dysfunction in case of long-term use;
• sets of several pills differing in composition to restore erection (Trial) and simultaneously solve two problems - erectile dysfunction and premature ejaculation (Professional).

Why is it worth buying generics for potency on our aggregator website?

1. By visiting us and entering the name of the drug in the search, you can find it at the best price, no need to go to the pharmacy, waste time and effort, our courier will do it for you and deliver the order in Moscow as soon as possible.
2. Using the services of our company, you can buy generics in Moscow wholesale and retail at low prices, as well as dietary supplements to improve erection, condoms, beauty and health products delivered from Moscow pharmacies.
3. We offer a flexible loyalty system for regular customers, after the first purchase you will receive a discount.
4. Secret promo codes and permanent promotions published on the site ensure that you always get low prices and favorable terms of service.
5. If you find prices lower than in our database, tell us where it is cheaper, and after checking the legality of the specified pharmacy, we will include it in the search.
6. Applications made on the site are accepted around the clock. Applications are accepted via a free hotline from 10:00 to 21:00 Moscow time.
7. Our clients have the opportunity to have a free consultation on the action of any drug from a professional pharmacist if you have questions about the dosage regimen and contraindications.
8. Convenient site search, comparison and analysis of prices for all offers on the Internet.
9. For every item we sell, we have necessary documentation, references and certificates.
10. When placing an order in Generics.RU, you can forget about embarrassing moments - you will no longer need to personally meet with a pharmacist to explain your problem. We blush for you, it's easy for us!

Amoxiclav: instructions for use and reviews