home→Treatment→ Sinaflan: instructions for use of ointment and gel. When will Sinaflan ointment help, and how can it be replaced? Sinaflan ointment - hormonal or not

Sinaflan: instructions for use of ointment and gel. When will Sinaflan ointment help, and how can it be replaced? Sinaflan ointment - hormonal or not

In this article, you can read the instructions for the use of hormonal medicinal product Sinaflan.

Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Sinaflan in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications were observed and side effects, possibly not declared by the manufacturer in the annotation. Synaflan analogues in the presence of existing structural analogues. Use for the treatment of eczema, neurodermatitis and pruritus in adults, children, as well as during pregnancy and lactation.

Sinaflan is a glucocorticosteroid for external use. It has anti-inflammatory, antiallergic, antiexudative and antipruritic action. When exposed to the skin, the marginal accumulation of neutrophils is prevented, which leads to a decrease in inflammatory exudate and the production of cytokines; inhibition of macrophage migration, reduction of infiltration and granulation processes.

Fluocinolone acetonide + excipients.

After absorption from the surface of the skin, it binds to plasma proteins and undergoes metabolism, which occurs mainly in the liver. Excreted by the kidneys.

Acute and chronic inflammatory and allergic skin diseases of non-microbial etiology, accompanied by dry skin:

seborrheic dermatitis;
eczema of various origins and localization;
neurodermatitis;
skin itching;
psoriasis;
sunburn;
insect bites.

Ointment for external use 0.025%.

Cream for external use.

Instructions for use and scheme of use

Adults and children over 2 years old externally.

Apply a small amount of the drug 2-4 times a day to the skin previously wiped with a swab moistened with an antiseptic liquid and rub it lightly. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease up to 25 days.

With limited lesions, to enhance the effect, the ointment can be used under an occlusive dressing. It is not allowed to use more than 2 g of ointment per day under a bandage. It is preferable to use the ointment for dry forms of dermatoses.

burning;
skin itching;
dry skin;
"steroid" acne;
folliculitis;
secondary immunodeficiency;
hypertrichosis;
alopecia, especially in women;
skin atrophy;
hirsutism, at the site of application of the drug;
telangiectasia;
purpura;
violation of pigmentation;
when applied to large surfaces, systemic manifestations are possible (gastritis, "steroid" gastric ulcer, adrenal insufficiency, Itsenko-Cushing's syndrome, "steroid" diabetes, striae, slowing down of reparative processes).

hypersensitivity;
skin manifestations of syphilis;
lupus;
"diaper" rash;
rosacea (pimples);
extensive psoriatic plaques;
anogenital itching;
skin infections caused by bacteria, viruses, fungi;
pyoderma;
chickenpox;
herpes;
actinomycosis;
blastomycosis;
sporotrichosis;
trophic ulcers of the lower leg associated with varicose veins;
erosive and ulcerative lesions of the gastrointestinal tract;
wounds at the application sites;
skin cancer;
nevus;
atheroma;
melanoma;
hemangioma;
xanthoma;
sarcoma;
pregnancy;
lactation period;
children's age (up to 2 years).

Use during pregnancy and lactation

Contraindicated: pregnancy, lactation.

Contraindicated in children under 2 years of age. The duration of use in children should not exceed 5 days.

Apply only in short courses on small areas of the skin. The drug should not be applied to the face. Avoid getting the drug in the eyes. The duration of use in children should not exceed 5 days. It is recommended to wear loose clothing during treatment.

In patients with acne vulgaris or rosacea during treatment, an exacerbation of the disease is possible. To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

Use with caution in persons with existing atrophic skin changes, especially in the elderly.

Compatible with antimicrobial drugs.

Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations.

Diuretic drugs (other than potassium-sparing ones) increase the risk of hypokalemia.

During treatment with glucocorticosteroids, vaccination and immunization should not be carried out, due to the immunosuppressive effect of the drug.

Analogues of the drug Sinaflan

Structural analogues for the active substance:

Sinaflan ointment - what it is used for and how to use

Sinaflan ointment is a yellow or light yellow topical glucocorticosteroid. The drug helps with skin pathologies that are not caused by bacterial infections. Sinaflan effectively removes skin inflammatory reactions, but has some contraindications. Let's find out in more detail the characteristics of the ointment, possible side effects and under what circumstances dermatologists advise using it.

Sinaflan ointment - hormonal or not?

The active active component of Sinaflan ointment is fluocinolone acenotin, which is a synthetic glucocorticoid. It interferes with the synthesis of collagen and protein, exerting a depressant effect on the immune system. Thus, Sinaflan is a hormonal medicine. When choosing a course of treatment, this fact must be taken into account, because the drug can be addictive and lead to various complications.

Release form and composition of Sinaflan ointment

Sinaflan ointment is available in aluminum tubes of 10 and 15 grams. Each tube is packed in a cardboard box containing detailed instructions by application hormonal drug. This tool can be produced in the form of a gel, cream, liniment. The composition of the ointment includes the main active ingredient of fluocinolone acetonide and excipients:

The ointment has antiallergic, antipruritic, anti-inflammatory action. When the drug acts on the skin, there is a decrease in the production of cytokines, the prevention of marginal accumulation of neutrophils, the processes of granulation and infiltration decrease, and the risk of developing exudative reactions decreases. Sinaflan from the surface of the skin is absorbed into the capillaries, enters the bloodstream, then binds to the plasma. Then, passing through the liver, it breaks down and is excreted by the kidneys from the body.

What ointment helps from: indications for use

Sinaflan topical ointment helps with non-microbial skin inflammations, allergic reactions on the skin, accompanied by itching. The main indications for use are the following pathologies:

Eczema.
Atopic dermatitis.
Psoriasis.
Neurodermatitis.
Lichen planus.
Hives.
Seborrheic dermatitis.
Lupus erythematosus.
Polyform erythrema.

Sinaflan ointment is also used for sun or light household burns, with bites of various insects, or if there is itching after bites. For more effective therapy infectious diseases often ointment is prescribed for use in conjunction with antimicrobial and antifungal drugs. The use of Sinaflan ointment gives positive results in itching anus or genitals.

Instructions for use and dosage

The drug should be used externally, applying a thin layer of ointment to the affected area, wiped with a disinfectant beforehand. The product should be rubbed into the skin with light massaging movements daily from 2 to 4 times. The course of treatment depends on clinical picture, but it is better if it is not long (no more than 14 days). The doctor extends the duration of therapy on an individual basis. It is allowed to apply gauze bandages to enhance the therapeutic effect.

Judging by the feedback from patients, Sinaflan ointment in case of overdose or when used for a long time can cause such side effects, as atrophy of the skin or re-infection of the skin. There may also be perioral dermatitis, the occurrence of acne, rash, dry skin, as well as hypertrichosis, telangiectasia, hirsutism, pigmentation disorders, exacerbation of the disease on the background of an overdose.

Absolute contraindications to the use of the ointment include patients with fungal, viral, microbial skin pathologies, people with intolerance to the components of the hormonal agent. Do not use the drug in patients with skin manifestations of syphilis, skin tuberculosis, cancerous tumors or trophic ulcers. Caution should be exercised when treating young people with corticosteroid during puberty.

Application during pregnancy

Sinaflan ointment during pregnancy can only be prescribed by a doctor who considers the benefit to the mother greater than the risk to the fetus. Many gynecologists are trying to replace the drug with analogues, believing that pregnancy and Sinaflan are not compatible. After all, this hormonal medicine has many contraindications and adverse reactions, so doctors try not to risk the health of the mother and child. If it is necessary to use the drug during breastfeeding(lactation), then feeding the child for this period should be stopped.

special instructions

Sinaflan ointment is not prescribed to children who have not reached the age of 12 years. The duration of treatment for adolescents should not exceed 5 days, so as not to provoke adverse reactions of the body. The shelf life of the hormonal agent is 5 years. After this time, the use of the drug is prohibited.

The drug is sold in pharmacies without requiring a prescription from a doctor. How much does Sinaflan ointment cost? The price in Russian pharmacies varies from 20 to 30 rubles for a tube of 10 grams and from 55 to 65 rubles for a 15 gram ointment. The cost depends on the manufacturer, but differs slightly. Sinaflan ointment is produced by Russian pharmaceutical enterprises in St. Petersburg, Murom, Saransk, Nizhny Novgorod.

Analogues of ointment Sinaflan

Nitrofungin. An effective analogue that should be used for the treatment of fungal skin manifestations: eczema, candidiasis, trichophytosis, epidermophytosis.
Petroleum. Shown at chronic diseases skin (psoriasis, dermatitis), scalp, in the presence of an unpleasant smell of sweat, sprains, motion sickness.
Furkotsin. Cheap analogue Sinaflan used for the treatment of fungal and pustular diseases of the dermis, for the treatment of superficial wounds, abrasions, cracks.
Flucinar. Effectively fights against atrophic skin changes. Should be used for dermatitis, psoriasis, eczema.

Reviews

Anastasia, 29 years old: I'm tired of treating seborrheic dermatitis - medications help for 3-5 days, then red scaly spots on my face reappear. I denied hormonal drugs as best I could, but the time has come when I already agree to everything, just to look decent. Sinaflan ointment is my savior. Removes seborrheic manifestations for a day and for a long time.

Karolina, 35 years old: Sinaflan ointment is my emergency remedy for acne and pimples, which is always in my purse. Every pimple that appears on the face must be squeezed out by me, although this is not recommended by dermatologists. As a result, I always get a painful wound that does not heal for a long time. An emergency assistant in such cases is Sinaflan. After 3 applications at night, acne disappears without a trace.

Tatyana, 44 years old: Sinaflan helps to cope with the annual seasonal allergies. With the onset of cold weather, I am tormented by a pimply allergy that occurs on the back of my hand. First, small pimples grow, and then they begin to itch, itch, and peel off. At first I suffered from allergies from November to March, until I bought an ointment. Now all symptoms are gone in 3 days!

Ointment Sinaflan: instructions for use, reviews

Sinaflan is a highly effective external drug that is prescribed for the treatment of various inflammatory skin lesions of non-infectious etiology.

The tool has a very powerful effect and is characterized by the presence of side effects, so before you start using it, it is important to carefully read all its properties, indications, mechanism of action and other features indicated in the annotation.

The international name of this drug is fluocinolone acetonide, according to the main active ingredient.

Composition

The main active ingredient of the external drug Sinaflan is fluocinolone acetonide, the concentration of which is 0.25 mg per 1 g of the product.

In addition to the main active substance, the composition also contains a number of auxiliary components that manufacturers have added. They include:

anhydrous lanolin;
petrolatum;
propylene glycol;
stearic acid;
pentanol;
nipagin;
nipazole;
distilled water;
soft white paraffin;
ceresin;
benzyl alcohol.

Release form

The drug Sinaflan, intended for external use, is produced by the well-known Russian pharmaceutical company Nizhpharm.

Also presented are such options as Sinaflan-Akrikhin and Sinaflan-Fitofarm, the manufacturers of which are the Russian pharmacological company Akrikhin and the Ukrainian Fitopharm. These funds are made exclusively in the form of an ointment.

There is a definite difference between them appearance, texture and readings.

The shade of the ointment can vary from light to rich yellow. All other forms are characterized by a pale yellow color.

Sinaflan gel has a uniform light and transparent texture. It is most effective for lesions of the scalp.

Sinaflan cream is quickly absorbed and works effectively. It is most often prescribed for wet dermatoses.

The ointment of the same name has an oily homogeneous consistency. This form the drug most of all helps with dry dermatoses.

Liniment

Liniment looks like an ointment, but with a more liquid texture, which is due to the water base.

It melts easily at human body temperature.

Its main purpose is to treat dermatoses of all types. It is recommended to apply this remedy under a bandage.

The main indications of Sinaflan: what it is used for

The drug Sinaflan in any form of release effectively helps in the following cases:

from eczema, which can have different localization;
with psoriasis of the whole body, as well as the scalp;
with atopic dermatitis (we talked about the symptoms and treatments for atopic dermatitis here);
from herpes;
from depriving;
from sunburn;
from body itching;
from bites of mosquitoes and other insects, in particular, wasps, bees, fleas and midges;
with allergies, which is expressed in profuse skin rashes;
with hemorrhoids;
with sweating;
against fungus;
from age spots;
with photodermatitis;
with a cold on the lips;
with thrush;
with diathesis;
with synechia;
from pink lichen;
from contact dermatitis;
with chickenpox;
with onycholysis;
from body itching;
from scars.

Sinaflan effectively treats neurodermatitis, erythema multiforme, discoid lupus erythematosus, lichen planus and other skin inflammations that are characterized by non-infectious etiology.

Also, this tool has a pronounced anti-allergic effect.

Is it a hormonal ointment or not?

The pharmacological group to which Sinaflan belongs is glucocorticosteroids for external use. Therefore, this drug is hormonal. What are glucocorticoids you will learn in this article.

Its main purpose is to eliminate the manifestations of the inflammatory reaction of the skin.

One of the negative aspects of the use of a hormonal drug is the effect of addiction, in connection with which the drug withdrawal syndrome is rather difficult to tolerate.

Therefore, in order to reduce possible harm, it is necessary to use the drug in strict accordance with the instructions.

Instructions for use Sinaflan

All forms of Sinaflan topical preparation are intended for the treatment of allergic manifestations and chronic skin diseases, severe sunburn, first-degree thermal burns, as well as various skin lesions, the occurrence of which is in no way associated with infections, viruses and microbes.

The method of application is as follows - the agent is applied with the thinnest layer on small areas of the skin of the body. The frequency of use and duration of therapy depends on the degree of damage.

In the case of using occlusive dressings, the daily dosage of the drug should be no more than two grams.

In cosmetology, the gel and ointment can be used to combat acne during puberty, but they can be applied to skin areas that are less sensitive - arms, legs and back.

When using the drug for the face, especially with sensitive skin, the main danger may be atrophy of the skin and an increase in the intensity of the rash due to the withdrawal syndrome.

In gynecology, this drug is prescribed for synechia and thrush. In both cases, a small amount of the product should be applied to the labia.

Sinaflan is also used for cats and dogs. This drug is very effective for scabies and eczema.

The shelf life of Sinaflan is 5 years from the date of manufacture. After the expiration of this period, it cannot be applied.

Is it possible to use the drug for children and women during pregnancy

Due to the fact that Sinaflan is a hormonal drug, many people wonder if it is dangerous for children, especially for babies, as well as for pregnant women and for women during lactation.

In pregnant women, there is a risk that all the active substances contained in the preparation may first enter the bloodstream, and then into the uterus through the placenta.

In addition, the components of the drug can be absorbed with breast milk, so for the period of treatment, HB should be stopped.

Newborn babies, as well as children under one year old, are not allowed to use Sinaflan. Starting from the age of two, this drug can be used, but under strict doctoral supervision.

It is strictly forbidden to apply this remedy on the face of a child.

This publication will tell about what CMV infection is in children.

Medicine price: how much does it cost in Russian pharmacies

Being a drug from Russian manufacturers, Sinaflan in the form of an ointment, gel, cream and liniment has a low cost that is affordable for every consumer.

Depending on the form of release, the price of the drug can vary from ten to ninety rubles.

Analogues and substitutes

If it is impossible to use Sinaflan, other tablets, ointments and gels with similar properties can be used.

Among the main substitutes for this drug are Sinaflan Akrikhin, Sinaflan Fitopharm, Elocom, Hydrocortisone, Akriderm, Advantan, Levomekol and Prednisolone. It is important to familiarize yourself with all their properties in order to choose the best option.

Hydrocortisone is a hormonal topical drug that comes in the form of ointments, tablets, injections, and eye drops and ointments.

This remedy is prescribed for inflammatory processes of the skin, infected wounds, as well as weeping wounds that are difficult to heal. You can read more about the indications and instructions for using Hydrocortisone ointment here.

Akriderm is available as an ointment and cream based on betamethasone. Recommended for use in skin allergies and psoriasis.

Advantan is a highly effective German drug, presented in the form of an ointment, cream and skin light emulsion. The main active ingredient of this drug is methylprednisolone aceponate.

A feature of the drug Advantan is that it can be used for diaper rash and diathesis in babies, starting from 4 months of age.

Instructions for use of Advantan cream and ointment for children can be found at this link.

Levomekol is a drug that is produced in the form of an ointment that has a white color. It is characterized by a pronounced anti-inflammatory and dehydrating property, and therefore, it is prescribed for the treatment of purulent wounds.

Prednisolone is a synthetic glucocorticosteroid drug, presented in the form of tablets, ointment, and also a clear, colorless solution for injection.

This remedy is prescribed for autoimmune diseases, allergies, as well as pathologies of the adrenal glands.

Non-hormonal analogues of this drug include Fukortsin, Petroleum, Mikospor, Tetracycline and Prednisolone ointments.

Contraindications and side effects

It is forbidden to use the drug Sinaflan in any form in the following cases:

in childhood up to two years (but there are exceptions);
with streptoderma;
with diaper dermatitis;
with tuberculosis of the skin;
with individual intolerance to the components of the drug.

Side effects occur infrequently correct application drug. But the description indicates that in some cases there may be:

burning and itching directly at the site of application;
increased hair growth at the site of application;
violation of pigmentation of the skin;
head hair loss.

With too long use of the drug, gastritis, steroid diabetes mellitus, adrenal insufficiency, Itsenko-Cushing's syndrome, and ulcers on the mucous membranes of the digestive tract can develop.

The causes of development, symptoms, methods of treatment and photo toxicoderma in children are presented in this material.

Look for photos of herpes on the eye in this publication.

Overdose symptoms

When using Sinaflan in high dosages, endocrine system disorders, adrenal insufficiency, as well as excessive hair growth of the skin of the body are likely.

After the cessation of further use of the drug, negative manifestations disappear.

Reviews

Sinaflan analogues

Cheap analogues Sinaflan

Analogue by indication and method of application

Analogue in composition and indication

Analogue by indication and method of application

When calculating the cost of cheap Sinaflan analogues, the minimum price was taken into account, which was found in the price lists provided by pharmacies

Popular analogues Sinaflan

Analogue in composition and indication

Analogue by indication and method of application

This list of analogues of the drug is based on the statistics of the most requested drugs

All analogues Sinaflan

Analogues in composition and indications for use

The above list of analogues of drugs, in which Sinaflan substitutes are indicated, is the most suitable, since they have the same composition of active ingredients and match the indications for use

Analogues by indication and method of application

Different composition, may coincide in indication and method of application

Sinaflan instruction

Ointment for external use

100 g of ointment contains the active substance fluocinolone acetonide 25 mg.

Sinaflan is a glucocorticosteroid for topical use. It has anti-inflammatory, antiallergic, antiexudative and antipruritic action. Reduces manifestations and eliminates the inflammatory skin reaction.

Inflammatory and allergic skin diseases of non-microbial etiology:

Eczema of various genesis and localization.

Other chronic forms inflammatory and allergic skin diseases accompanied by dry skin.

Hypersensitivity to the components of the drug.

Bacterial, viral, fungal skin diseases.

Anogenital itching, pyoderma, skin tumors.

Infectious skin diseases: skin manifestations of syphilis, skin tuberculosis, diaper rash, rosacea.

Extensive psoriatic rashes (plaques).

Trophic ulcers shins associated with varicose veins.

Pregnancy and lactation period.

Childhood(up to 1 year).

Use with caution in girls during puberty.

Dosage and administration

Outwardly. On the skin, previously wiped with a swab moistened with an antiseptic liquid, apply a small amount of the drug 2-4 times a day and lightly rub. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease - up to 25 days. With limited lesions, to enhance the effect, the ointment can be used under an occlusive dressing. It is not allowed to use more than 2 g of ointment per day under a bandage. It is preferable to use the ointment for dry forms of dermatoses.

Apply only in short courses on small areas of the skin. The drug should not be applied to the face. Avoid getting the drug in the eyes. The duration of the appointment in children should not exceed 5 days. It is recommended to wear loose clothing during treatment. In patients with acne vulgaris or rosacea during treatment, an exacerbation of the disease is possible. To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

Compatible with antimicrobial agents. Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations. Diuretic drugs (other than potassium-sparing ones) increase the risk of hypokalemia.

Symptoms: itching, burning of the skin at the site of application of the ointment, hyperglycemia, glucosuria, Itsenko-Cushing's syndrome.

Treatment: symptomatic against the background of the gradual withdrawal of the drug.

SINAFLANA OINTMENT analogues

We kindly ask you not to make a decision to replace SINAFLAN OINTMENT on your own, only on the instructions and with the permission of the doctor.

(56 offers from 20 to 37 UAH)

Price update date: 2 hours 52 minutes ago

CRYO-GEL REANIMATOR

Bruises, swelling, bruises;

Skin itching, as well as after depilation, shaving, in the post-peeling period;

Promotes healing of the skin with insect bites, light burns (from sunlight);

Pustular skin diseases;

To relieve tired legs;

MYCOSPOR

Mycospor cream, solution are indicated for: trichophytosis of smooth skin, trichophytosis of the hairy parts of the body, favus, mycosis of the hands, superficial candidiasis of the skin, rubrophytosis, mycosis of the feet, candidiasis of the nail folds, inguinal epidermophytosis, erythrasma, versicolor, genital candidiasis, microsporia, interdigital diaper rash, pityriasis versicolor.

NITROFUNGIN

FUSIMET OINTMENT

FUCORCIN

PETROLEUM

flu with fever, cough, chills, cold extremities; hearing loss; occipital headache.

The drug is good for people of medium build, who have an aggravation of symptoms in winter, in cold weather, during a storm, and a significant improvement with warming.

PULSATILLA COMPOSITE

BELOSALIK

multiform exudative erythema; red warty lichen; lichen planus; papulosquamous rashes with unspecified etiology; palmoplantar keratosis; pathological dryness of the skin; acquired ichthyosis, dermatoses with hyperkeratosis, peeling.

Belosalik lotion is used in the treatment of patients with oily skin, as well as with pathological changes hairy areas of the skin. Indications for the lotion: psoriasis (including the scalp); seborrheic dermatitis (including the scalp); neurodermatitis; lichen planus, localized on the scalp; ichthyotic, eczematous lesions of the skin under the hair.

MACLURA

DIMEXID

It is also prescribed for thrombophlebitis, diseases of the joints and spine, accompanied by inflammation and pain - inflammatory processes in the joints, including infectious-allergic nature (arthritis, rheumatoid, arthritis of Bechterew's disease), metabolic diseases of the joints and spine (osteoarthritis, osteochondrosis).

In gynecology, dimexide is used to treat infectious and inflammatory diseases of the external genital organs (vulvovaginitis).

When skin itching occurs, doctors prescribe a variety of remedies, most often these are creams for external use. Before buying, patients ask various questions, for example, what does Sinaflan ointment help with, or how to use it correctly. Such a drug is prescribed in various cases, so you should first study the instructions for use.

This ointment is a topical glucocorticosteroid. It is this type of drug that is practically the only suitable cure for dermatitis and other similar diseases. Usually, doctors prescribe to smear the skin with Sinaflan if the diseases are caused by something other than bacterial infections.

Release form and composition

You can buy Sinaflan ointment, instructions and reviews for which will be given below, in several ways. Usually it comes in aluminum tubes, but inside there can be either 10 or 15 grams of the product. The tubes themselves are packed in cardboard packaging, inside we put all the necessary documentation.

Existing release forms:

Ointment,
Gel,
Liniment.

The finished product has a uniform color, the shade of which can vary from light yellow to dark yellow. The active substance of the ointment is fluocinolone acetonide. Auxiliary components include:

Petrolatum,
Ceresin,
Lanolin anhydrous,
propylene glycol.

For each gram of the product, there are 250 micrograms of the active substance, so the ointment is sold at a concentration of 0.025%. The ratio of the components of the composition made it possible to create a product that is easy to apply and does not require rinsing. The medicine does not stain clothes and is completely absorbed.

What is the mechanism of influence based on?

In the process of considering Sinafal, most often people ask if it is a hormonal ointment or not. To answer, it is enough to turn to the composition again. Active ingredient, fluocinol acetonide, is a synthetic glucocorticoid. The use of such a substance leads to inhibition of the production of protein and collagen. It affects the immune system.

This means that the described ointment is a hormonal remedy. The direct effect on the skin leads to the fact that neutrophils, a special type of granulocytic leukocytes, accumulate in it less. Reducing their number leads to:

Less production of pathological fluids,
Less penetration of harmful substances into the skin,
Slower movement of cells capable of digesting bacteria and dead particles.

All this causes the effect of the ointment on itching, burning, inflammation and allergic reactions. After Sinaflan is absorbed into the skin, it enters the capillaries and then into the blood. Here, substances bind to the plasma and gradually reach the liver, where metabolic processes begin. Ultimately, the components are excreted from the body with the help of the kidneys.

Who is prescribed the ointment?

This ointment for external use is used for various skin pathologies. Most often, it is prescribed for non-microbial inflammations and reactions of allergic origin, especially if they are accompanied by itching.

According to medical opinion, the remedy will help with eczema of any nature and many other diseases. Below is a list of pathologies that answer the question of what Sinaflan ointment is used for:

Psoriasis,
atopic,
All types of urticaria,
Toxidermia,
Scabies,
scabious lymphoplasia,
Neurodermatitis,
red,
red flat,
Polyform erythema.

However, the ointment is used not only in the case of the development of some serious skin disease. Sometimes it is smeared on the skin for insect bites, sun or thermal burns, and also to combat diaper rash. It is worth remembering that for the fastest and effective treatment an integrated approach is needed. A few helpful remedies will make it easier to get rid of unpleasant symptoms.

The drug is used to treat acute inflammatory diseases of the skin: from seborrheic eczema to itching of the anus and genitals. Sinaflan is used to facilitate the recovery processes of the skin after insect bites and burns.

How to use the ointment?

The instructions for Sinaflan ointment describe in detail how and in what situations it can be used. For example, if a simple skin itch occurs, it is enough to apply a small amount of the product to the affected area. It does not need to be rubbed, the substance is absorbed on its own.

How else is Sinaflan used:

For the treatment of eczema, bedsores, pruritus and psoriasis, a course of treatment is required, the duration of which should not exceed 12 days. The minimum course duration is 5 days. The medicine is applied three times a day.
To affect burns and bites, no more than two grams of the product is used. It is applied with a cotton swab to previously cleansed skin. The subsequent imposition of a non-tight bandage is acceptable.
On average, according to the instructions, liniment can be applied up to four times a day, and the average duration of the course is one week.

Sinaflan is not an ointment. Although some tend to apply it on the face to combat such a problem, the instructions for use do not include this aspect of use. Moreover, if the substance gets on the skin of the face or mucous membranes, it must be washed off as soon as possible. It is important to remember that the extension of the course is permissible only for medical purposes.

Sinaflan ointment should be applied in a thin layer on the damaged areas of the skin that have been previously washed and cleaned of contaminants. Doctors recommend rubbing the drug with light movements - this way it is better absorbed and begins to act faster.

Contraindications

Sinaflan ointment is a hormonal drug. This means that it can harm the body in case of improper or excessively prolonged use. Many people wonder if it is possible to give such an ointment to children. This is acceptable if the child is already over two years old, but in this case, you need to combine the medicine with baby cream in a ratio of 1 to 1.

The list of contraindications includes:

Skin cancer,
Purulent processes on the epithelium,
The presence on the skin of benign neoplasms called nevi,
streptoderma,
against the backdrop of a progressive
Dermal,
Diaper.

As in any other case, this remedy should not be used if individual intolerance to any component of the composition is possible. Adolescents during puberty, the drug should be used with great caution.

Note! Pregnancy is included in the list of relative contraindications.

The components of the composition are able to penetrate into the blood, placenta and breast milk. Therefore, the use of ointment during pregnancy is unacceptable. If the need for such treatment arose during the period of breastfeeding, then you will have to temporarily switch to artificial nutrition.

Possible side effects

You can avoid side effects by strictly following the treatment plan that the doctor has established. Otherwise, as well as in conditions of hypersensitivity, the following side effects may occur at the application sites:

Enhanced hair growth
Itching and burning
Acne and folliculitis.

Regardless of the site of application, a person can also develop hypertrichosis, and patients have experienced problems with skin pigmentation. If the drug is used for a long time, side effects associated with hormonal effects appear. Among them:

Ulcers on the mucous membranes of the digestive tract,
adrenal insufficiency,
Steroid
Syndrome Itsenko-Cushing.

Although Sinaflan is an allergy remedy, its use can lead to allergic contact dermatitis. The list of side effects for children includes stunted growth and development. The drug may aggravate chronic diseases, but most often this occurs due to abrupt discontinuation of treatment. Sinaflan is able to increase and lead to edema.

With prolonged application of Sinaflan to large areas of the skin, the occurrence of systemic side effects is very likely, such as a hypofunctional disorder of the adrenal glands, a "steroid" stomach ulcer

Price and analogues

Before buying Sinaflan, people study how much such a medicine costs. For a package of 10 grams, which is shown in the photo below, you can pay 20-30 rubles, depending on the region. The price of a tube with 15 g of the drug is usually a little over 65 rubles. The ointment is produced by Russian enterprises, which are located in different cities, such as St. Petersburg, Nizhny Novgorod and Murom.

Possible analogues of Sinaflan:

Petroleum. It is used to combat chronic skin pathologies, such as dermatitis and psoriasis. In addition, it helps with sprains and seasickness.
Celestoderm. It has almost the same list of indications for use as Sinaflan.
Flucinar. It is usually prescribed for atrophic changes in the skin. Suitable for the treatment of eczema, psoriasis and dermatitis.
Nitrofungin. Most often, they turn to him if the disease was caused by fungi. For example, they are treated with epidermophytosis and trichophytosis.

Furkotsin can be attributed to cheap analogues. The tool fights lesions caused by fungi, especially if pus is present. Furcocin is suitable for the treatment of mechanical damage.

Ointment from light yellow to yellow.

Pharmacotherapeutic group

Highly active corticosteroids (group III). ATX code: D07AC04.

pharmachologic effect

Glucocorticosteroid for external use. It has anti-inflammatory, antiallergic, antiexudative and antipruritic action. Reduces manifestations and eliminates the inflammatory skin reaction.

Pharmacokinetics

After absorption from the skin surface, it binds to plasma proteins and is metabolized in the liver to form inactive metabolites. It is excreted mainly by the kidneys.

Indications for use

For the short-term treatment of inflammatory and allergic skin diseases that respond to local glucocorticosteroids and proceed with persistent itching or hyperkeratosis.

Anhydrous, fat-containing ointment Sinaflan is preferred for dry skin and chronic processes.

Contraindications

Hypersensitivity to the components of the drug; bacterial, viral, fungal skin diseases - pyoderma, chicken pox, herpes, actinomycosis, blastomycosis, sporotrichosis; skin manifestations of syphilis, skin tuberculosis, diaper rash, rosacea, extensive psoriatic rashes (plaques), anogenital itching; trophic ulcers of the lower leg associated with varicose veins, erosive and ulcerative lesions of the gastrointestinal tract, wounds at the application sites; skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma; pregnancy and lactation, children's age (up to 2 years).

Dosage and administration

The drug is intended for topical use only. Apply a small amount of the drug 1-2 times a day and lightly rub. Children over 2 years of age are used with caution 1 time per day under medical supervision. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease - no more than 2-3 weeks. Avoid applying the drug to large (more than 20% of the body surface) lesions. Perhaps the joint use of Sinaflan ointment with non-drug ointment, while Sinaflan ointment is applied once a day 12 hours after applying the non-drug ointment. Do not apply ointment under an occlusive dressing.

Children more sensitive than adults topical application glucocorticosteroids may penetrate the drug into the body. Therefore, Sinaflan ointment is used briefly (no more than 5 days) and with the lowest effective dose in children. In children, the drug should be used only for small areas of the skin (up to 10% of the body surface area). It is not allowed to apply ointment on the face of a child.

Side effect

Grade unwanted effects based on the following frequency data: very common (≥ 1/10), common (≥ 1/100 to From the skin and subcutaneous tissue:

Infrequently: urticaria, allergic contact dermatitis, skin irritation, striae (band-like skin atrophy), maculopapular rash, skin maceration at the application sites, perioral dermatitis, furunculosis. It is possible to develop secondary infectious skin lesions and atrophic changes in it (burning, itching, dry skin, steroid acne, folliculitis).

With prolonged use, skin atrophy, local hirsutism, telangiectasia, purpura, pigmentation disorders, hypertrichosis, alopecia are possible, especially in women.

From the digestive system:

Unknown: when applied to large areas of the skin, gastritis, steroid stomach ulcers are possible.

Endoc siderinny system:

Unknown: hyperglycemia. When applied to large areas of the skin, systemic manifestations are possible: adrenal insufficiency, Itsenko-Cushing's syndrome, steroid diabetes mellitus.

From the immune system:

Unknown: decrease in body resistance. With prolonged use, the following are possible: secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of the infectious process, development of opportunistic infections), slowing down of reparative processes.

From the sidetheycardiovascularsystems:

Unknown: arterial hypertension possible development of edema.

In the event of adverse reactions, including those not listed in given instructions, you should stop using the drug and consult a doctor chu.

Overdose

Symptoms: itching, burning of the skin at the site of application of the drug, gynerglycemia, glucosuria, Itsenko-Cushing's syndrome.

Treatment: symptomatic against the background of the gradual withdrawal of the drug.

Precautionary measures

Use the drug with caution in girls during puberty. Apply only in short courses on small areas of the skin. It is recommended to wear loose clothing during treatment.

In patients with acne vulgaris or rosacea during treatment, an exacerbation of the disease is possible.

To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

If the drug causes symptoms of irritation or allergic skin reactions (skin itching, burning or redness), its use should be stopped immediately. With prolonged use on a large surface of the body, the frequency of manifestation of side effects and the possibility of developing edema, hypertension, hyperglycemia, and a decrease in body resistance increase.

When using occlusive dressings, due to increased bioavailability, it is possible to develop general resorptive effects characteristic of GCS. With external use of the drug, the following are possible: a decrease in the production of ACTH by the pituitary gland, inhibition of the adrenal gland-pituitary gland, a decrease in the level of cortisol in the blood and the development of Itsenko-Cushing's iatrogenic syndrome, which disappears after discontinuation of the drug. Periodic monitoring of adrenal function is shown by determining cortisol in the blood and urine after stimulation of the adrenal glands with ACTH with prolonged use. If an infection develops at the site of application of the drug, treatment should be discontinued and appropriate antibacterial or antifungal treatment should be carried out. The drug should be used with caution in the presence of subcutaneous tissue atrophy, mainly in elderly patients. Avoid getting the drug in the eyes, mucous membranes and wounds. Do not use on breast skin. Use with extreme caution in the treatment of patients with psoriasis, since topical use of glucocorticosteroids in psoriasis can be dangerous due to relapse of the disease caused by the development of drug resistance, the risk of generalized pustular psoriasis and systemic toxicity caused by skin dysfunction. On the skin of the face, as well as on the skin of the groin and armpits, apply only in cases of special need, taking into account the increased absorption and high risk the development of side effects (telangiectasia, oral dermatitis), even after a short use. During treatment, it is not recommended to vaccinate against smallpox, as well as to carry out other types of immunization (especially with prolonged use on large areas of the skin) due to the possible lack of an adequate immunological response in the form of the production of appropriate antibodies. Contains lanolin. May cause local skin reactions (eg contact dermatitis). Contains propylene glycol. May cause skin irritation. When using the ointment in the genital or anal area, due to the Vaseline excipient, a decrease in strength and rupture of latex condoms may occur.

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation is contraindicated.

Use in children

Because the surface area/body weight ratio is higher in children than in adults, they are at higher risk of systemic side effects of glucocorticosteroids, including hypothalamic-pituitary-adrenal axis dysfunction and Cushing's syndrome. Corticosteroid therapy can have side effects on the growth and development of children. Periodic monitoring of the function of the adrenal cortex is shown by determining cortisol in the blood and in the urine after stimulation of the adrenal glands with ACTH. The use of the drug in children under the age of 2 years is contraindicated.

Influence atability to drive vehicles or other mechanisms

No data.

Best before date

5 years. Do not use the drug after the expiration date.

Terms of dispensing from pharmacies

On prescription.

Manufacturer/organization accepting claims

Sinaflan ointment - hormonal or not?

The active active component of Sinaflan ointment is fluocinolone acenotin, which is a synthetic glucocorticoid. It interferes with the synthesis of collagen and protein, exerting a depressant effect on the immune system. Thus, Sinaflan is a hormonal drug. When choosing a course of treatment, this fact must be taken into account, because the drug can be addictive and lead to various complications.

Release form and composition of Sinaflan ointment

Sinaflan ointment is available in aluminum tubes of 10 and 15 grams. Each tube is packed in a cardboard box, which contains detailed instructions for the use of a hormonal preparation. This tool can be produced in the form of a gel, cream, liniment. The composition of the ointment includes the main active ingredient of fluocinolone acetonide and excipients:

medical vaseline;
propylene glycol;
anhydrous lanolin;
ceresin.

What ointment helps from: indications for use

Sinaflan topical ointment helps with non-microbial skin inflammation, allergic reactions on the skin, accompanied by itching. The main indications for use are the following pathologies:

Eczema.
Atopic dermatitis.
Psoriasis.
Neurodermatitis.
Lichen planus.
Hives.
Seborrheic dermatitis.
Lupus erythematosus.
Polyform erythrema.

Sinaflan ointment is also used for sun or light household burns, with bites of various insects, or if there is itching after bites. For more effective treatment of infectious diseases, ointment is often prescribed for use in conjunction with antimicrobial and antifungal drugs. The use of Sinaflan ointment gives positive results with itching of the anus or genitals.

Instructions for use and dosage

The drug should be used externally, applying a thin layer of ointment to the affected area, wiped with a disinfectant beforehand. The product should be rubbed into the skin with light massaging movements daily from 2 to 4 times. The course of treatment depends on the clinical picture, but it is better if it is not long (no more than 14 days). The doctor extends the duration of therapy on an individual basis. It is allowed to apply gauze bandages to enhance the therapeutic effect.

Contraindications and side effects

Judging by the feedback from patients, Sinaflan ointment, with an overdose or when used for a long time, can cause side effects such as atrophy of the skin or re-infection of the skin. There may also be perioral dermatitis, the occurrence of acne, rash, dry skin, as well as hypertrichosis, telangiectasia, hirsutism, pigmentation disorders, exacerbation of the disease on the background of an overdose.

Application during pregnancy

Sinaflan ointment during pregnancy can only be prescribed by a doctor who considers the benefit to the mother greater than the risk to the fetus. Many gynecologists are trying to replace the drug with analogues, believing that pregnancy and Sinaflan are not compatible. After all, this hormonal medicine has many contraindications and adverse reactions, so doctors try not to risk the health of the mother and child. If it is necessary to use the drug during breastfeeding (lactation), then feeding the child for this period should be stopped.

special instructions

Price

Analogues of ointment Sinaflan

Nitrofungin. An effective analogue that should be used for the treatment of fungal skin manifestations: eczema, candidiasis, trichophytosis, epidermophytosis.
Petroleum. It is indicated for chronic diseases of the skin (psoriasis, dermatitis), scalp, in the presence of an unpleasant smell of sweat, sprains, seasickness.
Furkotsin. A cheap analogue of Sinaflan, used for the treatment of fungal and pustular diseases of the dermis, for the treatment of superficial wounds, abrasions, cracks.
Flucinar. Effectively fights against atrophic skin changes. Should be used for dermatitis, psoriasis, eczema.

Name:

Sinaflan (Sinaflanum)

Pharmacological
action:

Sinaflan- a drug of the group of topical glucocorticosteroids.
fluocinolone acetonide- a substance obtained synthetically, which has a pharmacological activity similar to glucocorticosteroids, has a high glucocorticoid activity and practically does not have a mineralocorticoid effect.

The drug molecule contains additional 2 fluorine atoms, which help to reduce local absorption and enhance anti-inflammatory action.

A drug when applied topically:
- antipruritic action;
- anti-allergic and anti-inflammatory action;
- promotes local vasodilation.

The main mechanism of action of the drug is the inhibition of phospholipase A2. Inhibition of the activity of this enzyme prevents the conversion of arachidonic acid into a pharmacologically active form.
By reducing the activity of arachidonic acid there is a decrease in the number of leukotrienes and prostaglandins, which are the main mediators of inflammation.

A drug by reducing the release of histamine from mast cells inhibits the development of hypersensitivity reactions.

When using the drug Sinaflan the risk of development of exudative reactions decreases, because active substance the drug contributes to the narrowing of the lumen of the vessels.

The drug affects protein metabolism, in particular, leads to a decrease in protein synthesis and collagen deposition.

When applied topically, the drug is well absorbed through the stratum corneum of the epidermis and accumulates in the dermis, pharmacologically significant concentrations of fluocinolone are determined in the dermis 15 days after application.

The drug is not biotransformed in the skin.
Systemic absorption is negligible, however, increases when the drug is applied to areas of the skin that are hypersensitive, including the face, skin folds, damaged areas of the epidermis.
Systemic absorption increases also when applying the drug Sinaflan under an occlusive dressing and with prolonged use of the drug on large areas of the skin.
In children and adolescents, systemic absorption of topical glucocorticosteroids is higher than in adults.

Indications for
application:

A drug used for skin diseases that require glucocorticosteroid therapy, including:
- psoriasis;
- lichen planus and discoid lupus erythematosus;
- seborrhea of the skin;
- eczematous lesions of various localization;
- neurodermatitis;
- allergic skin diseases and pruritus of various etiologies;
- first-degree burns, including sunburn;
- insect bites.

Mode of application:

Outwardly. On the skin, previously wiped with a swab moistened with an antiseptic liquid, apply a small amount of the drug 2-4 times a day and lightly rub.
Duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease - up to 25 days.

With limited lesions to enhance the effect, the ointment can be used under an occlusive dressing. It is not allowed to use more than 2 g of ointment per day under a bandage. It is preferable to use the ointment for dry forms of dermatoses.

Avoid getting the drug in the eyes. The duration of the appointment in children should not exceed 5 days. It is recommended to wear loose clothing during treatment.

In patients with acne vulgaris or rosacea against the background of treatment, an exacerbation of the disease is possible. To prevent local infectious complications, it is recommended to prescribe in combination with antimicrobial agents.

Side effects:

Telangiectasias;
- poststeroid vascular purpura;
- skin atrophy;
- stretching of the skin;
- hirsutism;
- hypertrichosis;
- perioral dermatitis;
- secondary infectious lesions of the skin.

For prolonged use and/or when applied to large surfaces possible systemic side effects.

Contraindications:

Hypersensitivity to the components of the drug.
- Bacterial, viral, fungal skin diseases.
- Anogenital itching, pyoderma, skin tumors.
- Infectious skin diseases: skin manifestations of syphilis, skin tuberculosis, diaper rash, rosacea.
- Extensive psoriatic rashes (plaques).
- Trophic leg ulcers associated with varicose veins.
- Pregnancy and lactation period.
- Children's age (up to 1 year).

Use with caution in girls during puberty.

Interaction
other medicinal
by other means:

Compatible with antimicrobials.
Reduces activity antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations. Diuretic drugs (other than potassium-sparing ones) increase the risk of hypokalemia.